Published: 27 Jul 2017 | Last Updated: 31 Jul 2017 09:24:54

A Comparative Physiology and Medicine symposium was held on 31 May 2017 at the RVC.

This day was to celebrate and reflect upon the scientific career of a leader of our profession, Alastair Robert (Bob) Michell. Bob was passionate about science, driven by curiousity and a burning desire to understand both the similarities and differences between veterinary species and humans. Comparative medicine was something he vigorously pursued as his academic discipline.

Programme (including memories of Bob by the speakers)


09.00 – 09.20 Registration and Coffee

09.25 – 09.30 Welcome from Professor Stuart Reid

09.30 – 09.50 Introduction (Professor Peter Lees)

Part I – Oral Rehydration Solutions (Chair – Dr David White)

09.50 – 10.20 Historical view of the concept of ORS and their development for use in calves
(Dr Harriet Brooks, University of Bristol) - Recording of Harriet's presentation

10.20 – 10.50 Diagnosis of acid base balance in diarrhoeic calves – implementation in practice
(Dr Dai Grove-White, University of Liverpool) - Recording of Dai's presentation

11.00 – 11.40 Coffee Break and poster viewing

Part 2a: Assessment of kidney function and comparative nephrology (Chair – Prof David Church)

11.40 – 12.10 Measurement of GFR – a historical perspective to state of the art
(Prof AM Peters, Brighton and Sussex Medical School) - Recording of Mike's presentation

12.10 – 12.40 Feline kidney disease – research at the RVC to achieve early diagnosis
(Prof Harriet M Syme, Royal Veterinary College) - Recording of Harriet's presentation

12.40 – 14.00  Lunch and poster viewing

Part2b: Assessment of kidney function and comparative nephrology (Chair – Dr Natalie Finch)

14.00 – 14.30 Measurement of GFR in the dog
(Dr Allison Gleadhill, Crab Lane Vets, Harrogate) - Recording of Alison's presentation

14.30 – 15.00  Use of iohexol clearance in dogs as a diagnostic test – does it help in early diagnosis of kidney disease
(Dr Ludovic Pelligand – Royal Veterinary College) - Recording of Ludovic's presentation

Part 3 – Hypertension (Chair – Prof Michael Herrtage)

15.00 – 15.30: Human hypertension and Genomics – current state of the art
(Prof Mark Caulfield, QMUL) - Recording of Mark's presentation

15.30 – 16.00  Tea and poster viewing

16.00 – 16.30: Hypertension in the dog
(Dr Angela Bodey, Abbey House Veterinary Hospital, N Yorks) - Recording of Angela's presentation

16.30 – 17.00 Hypertension in the cat – an overview of RVC research
(Prof Jonathan Elliott, Royal Veterinary College) - Recording of Jonathan's presentation

17.00 – 17.20 Closing remarks (BVA/RCVS Presidents) - Recording of Stephen May's closing remarks


Posters: on display in the Lightwell

Title of poster



Seasonal Variation in Blood Nitrite Concentration in Previously Laminitic and Non-Laminitic Ponies

Liz Finding


Evidence for updating feeding policies for pre-weaned dairy heifers in the calf

Claire Wathes


Investigation of synovial fluid on tendon injuries

Giulia Sivelli


Developing strategies to improve the healing of equine tendons using a surgical model

Ise Francois


Radha Desai AND Danilo Faccenda


Muscle physiology/testing therapies for DMD

Dominic Wells/Ornella Cappellari


Modelling the rodent hindlimb.

Dominic Wells/Ornella Cappellari


Secondary osteons scale allometrically in mammalian limb bones

Alessandro Felder


Vascular calcification and bone formation: are they the same?

Jessal Patel


Establishing comparable conditions to study vascular calcification and bone mineralisation

Lucy Bourne


Mechanical manipulation of the tendon stem cell niche

Neil Marr


Interaction between inflammation and mechanical loading in endochondral ossification

Astrid Novicky


Effect of Piezo2 on osteoarthritis and the associated pain

Freija ter Heegde


ControllingCartilage to Bone Transitions for Improved Treatment of Bone Defects and Osteoarthritis: the role of in vivo modulation of mechanical signals

Soraia Silva


  • Fracture-induced bone pain in a mouse model of femoral fracture
  • Immunohistochemical staining of a-klotho protein in feline kidney tissue

Ran Magnúsdóttir AND Henk van den Broek


The cat as a model of renal interstitial fibrosis: Characterisation of primary cultures of feline tubular epithelial cells.

Jack Lawson


  • Fibroblast growth factor 23 and symmetric dimethylarginine in feline chronic kidney disease
  • B2 or not B2 mitral valve disease differentiating between stable and progressive cases

Hannah Sargent and Jenny Wilshaw


Breed, coat colour and hair length as risk factors for feline hyperthyroidism

Victoria Crossley


Comparative pharmacodynamics of oxytetracycline, tetracycline and doxycycline in calf respiratory pathogens: Matrix and drug effect

Andrew Mead


Dynamic pharmacometrics: Hollow-fibre infection PK PD modelling of veterinary antimicrobials

Andrew Mead


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