Simon participates in the clinical diagnostic service of the RVC (post mortem and surgical biopsy work), is involved in training of residents in anatomic and clinical pathology and has a wide range of publications in collaboration with clinical colleagues within and outwith the RVC.
He is part of an expert panel of pathologists providing a diagnostic histopathology service to the Texas A&M University Gastrointestinal Laboratory.
Simon has a range of research interests, principally infectious respiratory diseases and gastrointestinal diseases of dogs. Simon's PhD was studying a novel betacoronavirus (CRCoV) causing infectious respiratory disease in dogs. He is currently leading a multidisciplinary team to improve diagnostics for canine infectious respiratory disease ('kennel cough') and has many other collaborative research interests including compative cancer pathology and ocular pathology. Simon is a Visiting Scientist/Consultant in Experimental Histopathology at the Francis Crick Institute providing pathology support and expertise to a number of research groups.