Dr Jonathan Williams
Department: Pathobiology and Population Sciences
Research Groups: CPCS (Research Programme)
Jonathan is a Senior Lecturer in Veterinary Anatomic Pathology at the Royal Veterinary College and Anatomic Pathology Residency Director. He is a Diplomate of the European College of Veterinary Pathologists (ECVP) and a Royal College of Veterinary Surgeons (RCVS) and European (EBVS) Recognised Specialist in Veterinary Pathology. He has also completed the Postgraduate Certificate in Veterinary Education and is a Fellow of the Higher Education Academy (FHEA).
Jonathan graduated from Bristol Vet School in 2005. He spent a brief time in mixed practice and then started a residency in veterinary pathology in 2006 at Liverpool Vet School. He became a Diplomate of the European College of Veterinary Pathologists in 2010 and a clinician teacher at Leahurst Surveillance Centre. He completed his PhD investigating Pathological Epithelial Cell Shedding in the Small Intestine in 2013. He then became a post-doctoral researcher investigating NF-κB signalling in IBD until he moved to the RVC as Lecturer in Veterinary Anatomic Pathology in 2015. He is the Anatomic Pathology Residency Director and has previously been Intra Mural Rotations Director. Jonathan is a member of the of the European College of Veterinary Pathologists (ECVP) and Innovation and New Technologies Task Force , European Society of Veterinary Pathologists (ESVP), British Society of Veterinary Pathology (BSVP), British Society of Toxicological Pathology (BSTP) and previously education sub-committee scientific organiser for the BSTP Annual Scientific Meeting.
Jonathan’s research interests are in intestinal epithelial signalling and cell death mechanisms in the context of gut barrier dysfunction. He is particularly interested in intestinal epithilial dynamics and how intestinal bacterial populations interact with the epithelial and immune cell compartments in health and disease. He also has special interests in investigating micro-RNAs as biomarkers of disease, and in digital pathology and computational approaches to pathology.
Please follow this link to see my ORCID record
Jonathan is the Anatomic Pathology Residency Director and has previously been Intra Mural Rotations Director. Jonathan lectures on gastrointestinal, hepatic and pacreatic pathology as well as pathology of the endocrine system. He also lectures on the principles and applications of pathology on the Bachelor of Veterinary Medicine, Bachelor of Biological Sciences and Bachelor of Comaparative Pathology courses. His teaching responsibilities include coordinating and administering the anatomic pathology residency programme, supervising Senior Clinical Training Scholars in Veterinary Pathology that are preparing for specialist qualifications in pathology and research students. He is also the Principles of Pathology unit organiser and deputy leader for the Imaging of Disease Module (BSc Biological Sciences), and deputy leader for the applications of pathology module for the BSc in comparative pathology.
Jonathan participates in the clinical surgical biopsy and post mortem diagnostic service of the RVC, and is involved in training the senior clinical training scholars in anatomic pathology.
Jonathan is a member of the of the European College of Veterinary Pathologists (ECVP) and Innovation and New Technologies Task Force , European Society of Veterinary Pathologists (ESVP), British Society of Veterinary Pathology (BSVP), British Society of Toxicological Pathology (BSTP) and previously education sub-committee scientific organiser for the BSTP Annual Scientific and Pathology of Mouse Models of Disease Meeting.
A Multi-disciplinary Approach to Investigating Canine Diffuse Large B cell Lymphoma
We propose to better define genetic subtypes of canine lymphoma and characterising response to treatment of the different subtypes through a combination of more accurate phenotyping of lymphomas by integrating a) advanced image analysis b) genome sequencing, and c) total RNA sequencing (including micro-RNA sequencing).