My research interests are in the area of developing novel diagnostics for mycobacterial infections primarily tuberculosis in people and cattle, as well as Johne’s disease. The technology I have developed uses bacteriophages to target mycobacteria, resulting in detection within hours compared to the several weeks it takes to culture. Using these methods I hope to gain a better understanding of the pathophysiology of mycobacterial infections, as well as providing an alternative tool for detection. I also have an interest in the role of badgers in the spread of TB – as part of a Defra funded project. I am currently funded by a BloomsburySET (Research England) research fellowship.
Ross has a particular interest in microbial infections of the skin, whether caused by bacteria or fungi, and their role in the exacerbation of pruritic and allergic skin diseases, and in otitis externa and media.
My research interests are in the area of the genetic basis of virulence and host preference in members of the MTBC. I am particularly interested in the transcriptional regulation of virulence factors and antimicrobial resistance determinants in Mycobacterial species. I have worked for over 20 years with pathogenic Mycobacteria and my current group are funded by the BBSRC, DEFRA and the International Veterinary Vaccinology Network.
Anette is particularly interested in staphylococcal skin infection, antibiotic resistance and food hypersensitivity. Anette is also interested in the therapeutic options and management of MRSA and MRSP infections in companion animals and infection control in small animal practice. As well as supervising small animal dermatology cases Anette is involved with equine referral cases.
I joined the Kendall TB lab in 2017 to work on a BBSRC funded project to identify the genes required by TB, specifically bovine TB (M. bovis) to survive. I am combing my immunology and microbiology skills to identify and assess the genetic determinants of M. bovis fitness in the using the natural bovine host. I use transposon mutagenesis to create large genetic libraries in M. bovis for screening under different conditions. Surviving mutants are sequenced by transposon directed insertion sequencing (TraDIS) to discover genes required for survival. Using various in vitro and in vivo screening methods I hope to discover novel essential genes that will aid the design of future DIVA vaccines and therapies for TB. I am interested in host-pathogen interactions, particularly the very early events that lead to infection. I hold a PhD in Molecular Immunology and have research experience in industry, civil service and academia.