Department: Research Support Office

Campus: Camden

Research Groups: Cardiovascular and Inflammation Biology and Metabolism, Ecosystems Health, Immune Regulation and Cancer

Research Centres: RVC Quantitative Biology Resource

Ruby is Lecturer in Statistics at the RVC. She provides statistical support on study design and data analysis for academic staff. She is a Chartered Statistician (CStat) of the Royal Statistical Society.

See Ruby's People Page on the website for more information.

Yu-Mei Ruby Chang completed her B.Sc. at Tung-hai University in Taiwan, and gained her M.Sc. degree in Statistics and Ph.D. in Animal Sciences from University of Wisconsin-Madison. Upon completing her Ph.D., she was appointed to the post of Computational Geneticist in the Dairy Science Department, University of Wisconsin-Madison, where she provided statistical and computational assistance to students and faculty staffs, and she also participated in collaborative research in the area of statistical modelling and algorithm development with application to dairy cattle improvement programs.

She joined the Section of Epidemiology and Biostatics, Leeds Institute of Molecular Medicine, University of Leeds as a Research Fellow in 2006. She allied with scientists and clinicians on the genetic and epidemiological data analysis of melanoma studies.

Ruby joins the RVC as a Lecturer in Statistics/Biometry in 2009.

  1. Sargent, H J; Jepson, R E; Chang, Y-M; Biourge, V C; Bijsmans, E S; Elliott, J.
    Fibroblast growth factor 23 and symmetric dimethylarginine concentrations in geriatric cats.
    Journal of Veterinary Internal Medicine, 2019

  2. Conroy, M C; Brodbelt, D C; O'Neill, D G; Chang, Y M; Elliott, J.
    Chronic kidney disease in cats attending primary care practice in the UK: a VetCompass study.

  3. Covey, H L; Chang, Y M; Elliott, J; Syme, H M.
    Changes in thyroid and renal function after bilateral thyroidectomy in cats.
    Journal of Veterinary Internal Medicine, 2019

  4. Conroy, M; Chang, Y-M; Brodbelt, D; Elliott, J.
    Survival after diagnosis of hypertension in cats attending primary care practice in the UK.
    Journal of Veterinary Internal Medicine, 1-10. (2018)

  5. Van Den Broek, D H N; Chang, YM; Elliott, J; Jepson, R E.
    Prognostic importance of plasma total magnesium in a cohort of cats with azotemic chronic kidney disease
  6. Van Den Broek, D H N; Geddes, R F; Williams, T L; Chang, YM; Elliott, J; Jepson, R E.
    Calcitonin Response to Naturally Occurring Ionized Hypercalcemia in Cats with Chronic Kidney Disease.
  7. Lawrence J, Chang YM, Szladovits B, Davison LJ, Garden OA. 2013. Breed-specific hematological phenotypes in the dog: a natural resource for the genetic dissection of hematological parameters in a mammalian species. PLoS ONE 8(11): e81288. doi:10.1371/journal.pone.0081288
  8. Lee CE, Moss W, Chau FC, Chang YM, Johnson KE. 2013. Feasting in Fresh Water: Impacts of food concentration on freshwater tolerance and the evolution of food x salinity response during saline to freshwater invasions. Evolutionary Applications 6(4): 673–689.
  9. Lee K, Palacios Jimenez C, Alibhai H, Chang YM, Leckie P, Priestnall S, Mookerjee R, Jalan R, Davies N. 2013. A reproducible, clinically relevant, intensively managed, pig model of acute liver failure for testing of therapies aimed to prolong survival. Liver International 33 (4), 544-551
  10. Bränström R, Kasparian NA, Affleck P, Tibben A, Chang YM et al. 2012. Perceptions of genetic research and testing among members of families with an increased risk of malignant melanoma. European Journal of Cancer 48: 3052-62.
  11. Kasparian NA, Bränström R, Chang YM et al. 2012. Skin examination behavior: The role of melanoma history, skin type, psychosocial factors, and region of residence in determining clinical and self-conducted skin examination. /Archives of Dermatology (doi: 10.1001/archdermatol.2012.1817).
  12. HEZZELL MJ, BOSWOOD A, CHANG YM, MOONARMART W, SOUTTAR K, ELLIOTT J. 2012. The Combined Prognostic Potential of Serum High-Sensitivity Cardiac Troponin I and N-Terminal pro-B-Type Natriuretic Peptide Concentrations in Dogs with Degenerative Mitral Valve Disease. J Vet Intern Med Feb 2012. (doi: 10.1111/j.1939-1676.2012.00894.x)
  13. ALARCON P, VELASOVA M, WERLING D, STÄRK KDC, CHANG YM, NEVEL A, PFEIFFER DU, WIELAND B. 2010. Assessment and quantification of post-weaning multi-systemic wasting syndrome severity at farm level. Preventive Vet Med 98, 19-28.
  14. NEWTON-BISHOP JA, CHANG YM, ELLIOTT F, CHAN M, LEAKE S, KARPAVICIUS B et al. 2011. Relationship between sun exposure and melanoma risk for tumours in different body sites in a large case-control study in a temperate climate. European J of Cancer 47, 732-741.
  15. BRÄNSTRÖM R, KASPARIAN NA, CHANG YM, AFFLECK P, TIBBEN A, ASPINWALL LG et al. 2010. Predictors of Sun Protection Behaviours and Severe Sunburn in an International on-line study. Cancer Epidemiology, Biomarkers & Prevention 19: 2199-2210
  16. BRANSTROM R, CHANG YM, KASPARIAN N, AFFLECK P, TIBBEN A, ASPINWALL LG et al. 2010 Melanoma Risk Factors, Perceived Threat and Intentional Tanning: An International Online Survey. Euro J of Cancer Prevention 19,216-226.
  17. NEWTON-BISHOP JA, BESWICK A, RANDERSON-MOOR J, CHANG YM, AFFLECK P, ELLIOTT F, CHAN M et al. 2009. Serum 25-Hydroxyvitamin D3 levels are associated with Breslow thickness at presentation, and survival from melanoma. J Clin Oncology 27, 5439-5444.
  18. CHANG YM, BARRETT JH, BISHOP DT, ARMSTRONG BK, BATAILLE V, BERGMAN W et al. 2009. Sun exposure and melanoma risk at different latitudes: a pooled analysis of 5700 cases and 7216 controls. Int J Epid. 38, 814-830.
  19. CHANG YM, NEWTON-BISHOP JA, BISHOP DT, ARMSTRONG BK, BATAILLE V, BERGMAN W et al. 2009. A pooled analysis of melanocytic naevus phenotype and the risk of cutaneous melanoma at different latitudes. Int J Cancer, 124, 420-428.
  20. LEE CE, REMFERT JL, CHANG YM 2007. Response to selection and evolvability of invasive populations. Genetica 129, 179-192.
  21. GONDA MG, CHANG YM, SHOOK GE, COLLINS MT, KIRKPATRICK BW 2006. Genetic variation of Mycobacterium avium ssp. paratuberculosis infection in US Holsteins. J Dairy Sci 89, 1804-1812.
  22. CHANG YM, ANDERSEN-RANBERG IM, HERINGSTAD B, GIANOLA D, KLEMETSDAL G. 2006. Bi-variate analysis of number of services to conception and days open in Norwegian Red using a censored threshold{linear model. J Dairy Sci 89, 772-778.
  23. GONZALEZ-RECIO O, CHANG YM GIANOLA D, WEIGEL KA. 2005. Genetic analysis of number of inseminations to conception in Holstein cows using censored records and time-dependent covariates. J Dairy Sci 88, 3655-3662.
  24. HERINGSTAD B, CHANG YM, GIANOLA D, KLEMETSDAL G. 2005. Genetic analysis of clinical mastitis, milk fever, ketosis and retained placenta in the rst three lactations of Norwegian Red with a multivariate threshold model. J Dairy Sci 88, 3273-3281.

Ruby teaches introduction to basic statistics for the Wild Animal Health, Wild Animal Biology and One Health MSc courses. She also teaches introduction to basic statistics to PhD students. Ruby also provides advanced statistical training and one-to-one statistics consultancy to PhD students and academic staff.


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