Dr Ali Fouladi-Nashta
Department: Comparative Biomedical Sciences
Campus: Hawkshead
Research Groups: Sustainable Food Systems, IRLFS (Research Programme), CPCS (Research Programme)
Ali is a member of the Reproduction Research Group. His research is based on oocyte biology and embryology of domesticated and farm animal species and uterine embryo interaction and mechanism of embryo implantation.
Ali trained as a Veterinarian in Tehran University and served for about 7 years as a Lecturer in Animal Reproduction before moving to the United Kingdom for further education. He gained his MSc in 1995 and PhD in 1999 from the University of Edinburgh in Scotland.
Ali undertook at PhD at the Roslin Institute where he worked alongside Professor Keith Campbell, creator of Dolly the cloned sheep from differentiated cells. Following this he moved on to undertake post-doctoral work at the University of Manchester, investigating the role of Leukaemia Inhibitory Factor with Sue Kimber. Subsequently he joined Nottingham University as a Research Fellow working with Professor Bob Webb to investigate the effects of diet on oocyte & embryo quality in lactating dairy cows.
In June 2006, Ali accepted a Lectureship position at the Royal Veterinary College (Department of Veterinary Basic Sciences). His research in the area of female reproduction continues. He was promoted to Senior Lecturer position in 2012 and then to Reader position in September 2016.
During his time at the Roslin Institute Ali's studies established that improvement in cytoplasmic maturation of bovine oocytes improves the rate of blastocyst development (Fouladi-Nashta et al., 1998, Biology of Reproduction 59: 255-262).
At the University of Manchester Ali investigated the role of leukaemia inhibitory factor (LIF) on implantation of embryos in mice. Using LIF gene knocked-out mice he showed misregulation of signalling mechanisms and absence of changes in the uterine endometrium associated uterine receptivity (Fouladi-Nashta et al., 2005, Developmental Biology, 281:1-21) resulting in infertility. They also demonstrated that LIF inhibitor can effectively inhibit its effects on decidualisation of uterine stroma cells (Fouladi-Nashta et al., 2004, Journal of Endocrinology, 181: 477-492).
Whilst at Nottingham University Ali investigated the effects of diet on oocyte and embryo quality in lactating dairy cows. Diets can modify the profiles of hormones and local production of growth factors thereby influencing reproductive function (Fouladi-Nashta et al., 2007, Biology of Reproduction 77: 9-17). He developed diets which can promote reproductive cyclicity and also increase pregnancy rate in post-calving dairy cows (Garnsworthy et al., 2008). He also developed a simple and fast but reliable technique for assessment of blastocysts (Reproductive BioMedicine Online, 2005, 10: 497-502).
Since joining the RVC in 2006, I have supervised 15 PhD students, all of whom have successfully completed their projects within 3 to 4 years of registration. In addition, I supervised 4 Post-Doctoral (Post-Doc) fellows over the years of working at the RVC.
- Currently, I am supervising 2 PhD students at the RVC, and I am a co-supervisor for one PhD student started recently in Thailand.
Research Grants and Contracts
|
Dates |
Grant |
£ Value |
|
2024-2025 |
Co-applicant with Prof Jayasinghe at UCL |
30000 |
|
2023-2024 |
Innovation UK |
120000 |
|
2022-2025 |
Translational research on canine ART |
250,000 |
|
2021-2023 |
Commonwealth PhD studentship |
35280 |
|
2019-2023 |
Duchenne UK (co-applicant with Prof. Richard Piercy) |
253,826 |
|
2014-2019 |
FP7 Collaborative Project (FP7-KBBE-2013-7-single-stage) |
€8000000 |
|
2015-2016 |
Concept Development Partnership Fund in collaboration with Origio |
50000 |
|
2015-2016 |
Society for Reproduction and Fertility (SRF) Academic Fund |
8475 |
|
March-June 2015 |
Epiconcept short term scientific mission for Montserrat Roura |
€2500 |
|
2014-2015 |
BBSRC Follow on Fund |
157,000 |
|
2013-2014 |
BBSRC Pathfinder |
8000 |
|
2011-2014 |
Ministry of Science and Innovation, Spanish Government: MT Paramio and AA Fouladi-Nashta |
€140,000 |
|
2011-2014 |
BBSRC New Investigator Award |
420,000 |
|
2008-2009 |
ICUK partnership grant |
13,400 |
|
2006 |
Internal grant, Royal Veterinary College |
10000 |
|
2006 |
Central Research Fund, University of London equipment grant |
4270 |
Recent oral presentations
|
Dates |
Location |
Presentation |
|
20-24 May 2024 |
32nd World Buiatrics Congress 2024 |
Invited panel speaker; Title: Nutritional regulation of fertility in post-partum dairy cows |
|
5 Sept 2024 |
AETE 2024, Brescia, Italy |
Age related decline in oocyte hyaluronan; impact on oocyte maturation and embryo development. |
|
16-20 July 2024 |
Society for Study of Reproduction (SSR) annual meeting- Dublin, Ireland |
Studies on The Impact of Hyaluronidases and Low Molecular Weight Hyaluronan on Preimplantation Embryo Development, Morphokinetics, Pregnancy and Live birth rates in Sheep. SSR annual meeting |
|
04 July 2024 |
Estonia |
Size-dependent impact of hyaluronan on embryo development and pregnancy outcome |
|
21 October 2024 |
University of Florida- USA |
Size-dependent impact of hyaluronan on embryo development and pregnancy outcome, lessons from studies in cow and sheep. |
|
28 October 2024 |
University of Calgary- Canada |
Studies on the role of hyaluronan system in female fertility |
|
8-11 Jan 2020 |
Fertility 2020 Edinburgh, UK |
Hyaluronidase-2 changes morphokinetics of in vitro cultured bovine embryos” |
|
3-5 Jan 2019 |
Fertility 2019 Birmingham, UK |
Hyaluronidase as a biomarker predictor of human embryo quality and pregnancy outcome |
|
3-6 Jan 2018 |
Fertility 2018 Liverpool, UK |
Impact of VLWHA on sheep blastocyst formation in vitro, viability after cryopreservation and pregnancy rate after embryo transfer) |
- Ghafari F, Salavati M, Piercy R J, Fouladi-Nashta AA (2025) Beneficial effects of melatonin on canine oocyte nuclear maturation via reduction of oxidative stress. Reproduction Mar 14;169(4):e240388, doi: 10.1530/REP-24-0388. .
- Fouladi-Nashta AA, Ghafari F, Maalouf WE, Werling NJ, Jayasinghe SN (2024) Bio-electrosprayed bovine sperm remain viable and fertilize oocytes. Appl. Phys. Rev. 11, 031414 (2024) https://doi.org/10.1063/5.0207391.
- Mbegbu EC, Salavati M, Aka LO, Obidike IR, Tang JCY, Fraser WD, Hanson MA, Green LR, Fouladi-Nashta AA. Impact of Periconceptional and Gestational Vitamin D3 Restriction on Fetal Folliculogenesis and Anti-Mullerian Hormone Secretion Using Sheep as a Model. Reprod Domest Anim 59:e14717. doi: 10.1111/rda.14717.
- Samadi MS; Deldar H; Fouladi-Nashta AA (2024) Effect of Ratios of Linoleic and Alpha-Linoleic Fatty Acids in Diet of Lactating Dairy Ewes on Milk Composition and Quantity, Fatty Acid Profile and Some Plasma Metabolites”. Austin Journal of Veterinary Science and Animal Husbandry. Published on 14 March.
- Samadi MS; Chashnidel Y; Deldar H; Fouladi-Nashta AA (2024) Effects of Different Ratios of Linoleic to Linolenic Acids in Diets During Flushing Period on Blood Metabolites, Hormone Concentrations and Reproductive Performance of Zel Ewes. Austin Journal of Veterinary Science and Animal Husbandry. Published on 19th of March.
- Grelet C, Larsen T, Crowe MA, Wathes DC, Ferris CP, Ingvartsen KL, Marchitelli C, Becker F, Vanlierde A, Leblois J, Schuler U, Auer FJ, Köck A, Dale L, Sölkner J, Christophe O, Hummel J, Mensching A, Fernández Pierna JA, Soyeurt H, Calmels M, Reding R, Gelé M, Chen Y, Gengler N; GplusE Consortium including Fouladi-Nashta AA; Dehareng F. (2024) Prediction of key milk biomarkers in dairy cows through milk mid-infrared spectra and international collaborations. J Dairy Sci 07(3):1669-1684. doi: 10.3168/jds.2023-23843.
- Gerri C, McCarthy A, Scott, GM, Regin M, Stamatiadis P, Brumm S, Simon CS, Lee J, Montesinos C, Hassitt C, Hockenhull S, Hampshire D, Elder K, Snell P, Christie L, Fouladi-Nashta AA, Van de Velde H, Niakan KK. (2023) A conserved role of the Hippo signalling pathway in initiation of the first lineage specification event across mammals. Development 150(8):dev201112. doi:10.1242/dev.201112.
- Samadi MS, Chashnidel Y, Deldar H, Dirandeh E, Fouladi-Nashta AA (2023) Impact of Different Ratios of Linoleic and Alpha-Linolenic Acids during the Flushing Period of Zel Ewes: Blood Metabolites, Hormone Concentrations, and Reproductive Performance. Animals, 2023, 13, https://doi.org/10.3390.
- Cheng Z, Ferris C, Crowe MA, Ingvartsen KL, Grelet C, Vanlierde A, Foldager L, Becker F, Wathes DC, GplusE Consortium including Fouladi-Nashta AA (2023) Hepatic Global Transcriptomic Profiles of Holstein Cows According to Parity Reveal Age-Related Changes in Early Lactation. International Journal of Molecular Sciences. 24(12):9906. doi:10.3390/ijms24129906.
- Lewin TD, Fouladi-Nashta AA, Holland PWH. (2022) PRD-Class Homeobox genes in bovine early embryos: function, evolution, and overlapping roles. Mol Biol Evol. 39(5):msac098. doi: 10.1093/molbev/msac098.PMID: 35512670
- Kong CS, Ordoñez AA, Turner S, Tremaine T, Muter J, Lucas ES, Salisbury E, Vassena R, Tiscornia G, Fouladi-Nashta AA, Hartshorne G, Brosens JJ, Brighton PJ. (2021) Embryo biosensing by uterine natural killer cells determines endometrial fate decisions at implantation. FASEB J 35(4):e21336.
- Tremaine TD, Fouladi-Nashta AA. (2021) Steroid regulation of secreted phosphoprotein 1 (SPP1) expression in ovine endometrium. Reprod Fertil Dev. 33:257-269.
- Ataei Nazari S, Mohammadi Sangcheshme A, Fzalzadeh A, Bakhtiarizadeh MR, Assadi Alamouti A, Fouladi Nashta AA (2021 Evaluating the Sheep Oocyte In Vitro Developmental Competence and Expression of MicrorRNAs in Cumulus Cells in Response to Inflammatory Effects Induced by Lipopolysaccharide. Res Anim Prod 12: 118-125.
- Yousefian I, Zare-Shahneh A, Goodarzi A, Baghshahi H, Fouladi-Nashta AA. (2021) The effect of Tempo and MitoTEMPO on oocyte maturation and subsequent embryo development in bovine model. Theriogenology 176:128-136.
- Moghimi Khorasgani A, Moradi R, Jafarpour F, Ghazvinizadehgan F, Ostadhosseini S, Heydarnezhad A, Fouladi-Nashta AA, Nasr-Esfahani MH. (2021) Alpha-Lipoic Acid can overcome the reduced developmental competency induced by alcohol toxicity during ovine oocyte maturation. Cell J. 23:164-173.
- Awan MA, Arshad J, Rakha BA, Ansari MS, Waseem M, Fouladi-Nashta AA, Miller D, Akhter S. (2021) Sperm binding to hyaluronan is an excellent predictor of Nili-Ravi buffalo bull fertility. Andrologia. 2021 Apr;53(3):e13991.
- Karamzadeh-Dehaghani A, Towhidi A, Zhandi M, Mojgani N, Fouladi-Nashta AA. (2021) Combined effect of probiotics and specific immunoglobulin Y directed against Escherichia coli on growth performance, diarrhea incidence, and immune system in calves. Animal. 2021 Feb;15(2):100124.
- Zahedi V, Kohram H, Zeynodini S, Yousefi AR, Baghshahi H, Moradi-Shahrbabak M, Zhandi M, Assad Rad M, Fouladi-Nashta AA. (2021) Trends in Reproductive Status of Holstein Dairy Herds in Iran. IJAS 11: 497-505.
- Wathes DC, Cheng Z, Salavati M, Buggiotti L, Takeda H, Tang L, Becker F, Ingvartsen KI, Ferris C, Hostens M, Crowe MA; GplusE Consortium including Fouladi-Nashta AA. (2021) Relationships between metabolic profiles and gene expression in liver and leukocytes of dairy cows in early lactation. J Dairy Sci. 2021 Mar;104(3):3596-3616.
- Cheng Z, Buggiotti L, Salavati M, Marchitelli C, Palma-Vera S, Wylie A, Takeda H, Tang L, Crowe MA, Wathes DC; GplusE consortium including Fouladi-Nashta AA. (2021) Global transcriptomic profiles of circulating leucocytes in early lactation cows with clinical or subclinical mastitis. Mol Biol Rep. 2021 May;48(5):4611-4623.
- Wathes DC, Cheng Z, Salavati M, Buggiotti L, Takeda H, Tang L, Becker F, Ingvartsen KL, Ferris C, Hostens M, Crowe MA; GplusE Consortium including Fouladi-Nashta AA). (2021) Corrigendum to "Relationships between metabolic profiles and gene expression in liver and leukocytes of dairy cows in early lactation" (J. Dairy Sci. 104:3596-3616). J Dairy Sci. 2021 May;104(5):6327.
- Buggiotti L, Cheng Z, Salavati M, Wathes CD; GplusE Consortium including Fouladi-Nashta AA (2021) Comparison of the transcriptome in circulating leukocytes in early lactation between primiparous and multiparous cows provides evidence for age-related changes. BMC Genomics 22(1):693.
- Muhammad, A; Javeria, A; Bushra, R; Muhammad, A; Muhammad, W; Miller, D; Fouladi-Nashta, AA; Akhter, S. (2020) Binding to Hyaluronan is an Excellent Predictor of Nili-Ravi Buffalo Bull Fertility". Andrologia. 2021 Feb 2:e13991. doi: 10.1111/and.13991.
- Gerri, C; Mccarthy, A; Alanis-Lobato, G; Demtschenko, A; Bruneau, A; Loubersac, S; Fogarty, N M E; Hampshire, D; Elder, K; Snell, P; Christie, L; David, L; Van de Velde, H; Fouladi-Nashta, A; Niaken, K K Initiation of a conserved trophectoderm program in human, cow and mouse embryos. Nature, 587 (7834), 443-447. 2020.
- Atashi H, Salavati M, De Koster J, Crowe MA, Opsomer G; GplusE consortium including Ali A Fouladi-Nashta, Hostens M. (2020) Genome-wide association for metabolic clusters in early-lactation Holstein dairy cows. J Dairy Sci. 2020 Jul;103(7):6392-6406.
- Foldager L, Gaillard C, Sorensen MT, Larsen T, Matthews E, O'Flaherty R, Carter F, Crowe MA, Grelet C, Salavati M, Hostens M, Ingvartsen KL, Krogh MA; GplusE Consortium including Ali A Fouladi-Nashta. (2020) Predicting physiological imbalance in Holstein dairy cows by three different sets of milk biomarkers. Prev Vet Med. 179:105006.
- Grelet, C; Vanlierde, A; Hostens, M; Foldager, L; Salavati, M; GplusE Consortium including Fouladi-Nashta, AA. et al. (2019) Potential of milk mid-IR spectra to predict metabolic status of cows through blood components and an innovative clustering approach. Animal, 13;3:649-658.
- De Koster, J; Salavati, M; Grelet, C; Crowe, M A; Matthews, E; O'Flaherty, R; Opsomer, G; Foldager, L; Hostens, M, GplusE Consortium including Fouladi-Nashta, AA et al. (2019) Prediction of metabolic clusters in early-lactation dairy cows using models based on milk biomarkers. J Dairy Sci, 102;3:2631-2644.
- Mbegbu E C. , OBIDIKE Ikechukwu R. FOULADI-and apoptosis-related NASHTA Ali A. (2019) Immunohistochemical detection of VASA antigen and apoptosis-related DNA fragmentation in ovaries of sheep fetuses prenatally exposed to vitamin D deficiency. Acta Veterinaria-Beograd 2019, 69 (3), 262-274.
- Marei, W F A; Khalil, W A; Pushpakumara, A P G; El-Harairy, M A; Abo El-Atta A M A; Wathes, D C; Fouladi-Nashta, A A.Polyunsaturated fatty acids influence offspring sex ratio in cows. International Journal of Veterinary Science and Medicine, 2018
- Hanousek K, Salavati M, Fouladi-Nashta A. (2018) Effect of horse gender on British Eventing competition performance: an observational study between 1998 and 2016. Vet Rec. 2018 Mar 23. pii: vetrec-2017-104719. doi: 10.1136/vr.104719
- Tremaine TD, Fouladi-Nashta AA. (2018) Immunolocalization of angiogenic growth factors in the ovine uterus during the oestrus cycle and in response to Steroids. Reprod Domest Anim. 2018 Mar 5. doi: 10.1111/rda.13156.
- Soto-Heras S, Roura M, Catalá MG, Menéndez-Blanco I, Izquierdo D, Fouladi-Nashta AA, Paramio MT. (2018) Differential proteomic profiling of endometrium and plasma indicate the importance of hydrolysis in bovine endometritis. J Dairy Sci. 100:9324-9337.
- Husna AU, Azam A, Qadeer S, Awan MA, Nasreen S, Shahzad Q, Fouladi-Nashta A, Khalid M, Akhter S. (2017) Sperm preparation through Sephadex™ filtration improves in vitro fertilization rate of buffalo oocytes. Reprod Domest Anim. 2018 Apr;53(2):377-384. doi: 10.1111/rda.13117. Epub 2017 Dec 14.
- Goodarzi A, Zare Shahneh A, Kohram H, Sadeghi M, Moazenizadeh MH, Fouladi-Nashta A, Dadashpour Davachi N. Effect of melatonin supplementation in the long-term preservation of the sheep ovaries at different temperatures and subsequent in vitro embryo production. Theriogenology. 2018 Jan 15;106:265-270. doi: 10.1016/j.theriogenology.2017.10.009.
- Zhang SD, Dong SW, Wang DS, Oguejiofor CF, Fouladi-Nashta AA, Yang ZQ, Yan ZT. (2017) Differential proteomic profiling of endometrium and plasma indicate the importance of hydrolysis in bovine endometritis. J Dairy Sci. 2017 Nov;100(11):9324-9337. doi: 10.3168/jds.2016-12365. Epub 2017 Sep 13.
- Roura M, Catalá MG, Soto-Heras S, Hammami S, Izquierdo D, Fouladi-Nashta A, Paramio MT. (2017) Linoleic (LA) and linolenic (ALA) acid concentrations in follicular fluid of prepubertal goats and their effect on oocyte in vitro maturation and embryo development. Reprod Fertil Dev. doi: 10.1071/RD17174. [Epub ahead of print]
- Soto-Heras S, Roura M, Catalá MG, Menéndez-Blanco I, Izquierdo D, Fouladi-Nashta AA, Paramio MT (2017) Beneficial effects of melatonin on in vitro embryo production from juvenile goat oocytes. Reprod Fertil Dev. 2017 Jun 19. doi: 10.1071/RD17170. [Epub ahead of print]
- Fouladi-Nashta AA, Raheem KA, Marei WF, Ghafari F, Hartshorne GM (2016). Regulation and roles of hyaluronan system in mammalian reproduction. Reproduction 153 (2):R43-R58.
- Marei WFA, Wathes DC, Raheem KA, Mohey-Elsaeed O, Ghafari F, Fouladi-Nashta AA (2016). Influence of hyaluronan on endometrial receptivity and embryo attachment in sheep. Reprod Fertil Dev. 2017 Sep;29(9):1763-1773. doi: 10.1071/RD16232.
- Marei WF, Tremaine T, Salavati M, Khalid, M and Fouladi-Nashta AA. (2016) Hyaluronan and hyaluronidase, which is better for embryo development? Theriogenology. 2016 Sep 1;86(4):940-948.
- Raheem KA, Marei WFA, Campbell BK, Fouladi-Nashta AA. (2016) In vivo and in vitro studies of MUC1 regulation in sheep endometrium. Theriogenology 85:1635-1643.
- Yousefi AR, Kohram H, Zare Shahneh A, Zamiri MJ, Fouladi-Nashta AA. (2016) Effects of dietary supplementation of pioglitazone on metabolism, milk yield, and reproductive performance in transition dairy cows. Theriogenology. 2016 Jan 19. doi:10.1016/j.theriogenology.2016.01.015.
- Oguejiofor CF, Cheng Z, Abudureyimu A, Fouladi-Nashta AA, Wathes DC. (2015) Global Transcriptomic Profiling of Bovine Endometrial Immune Response In Vitro. I. Effect of Lipopolysaccharide on Innate Immunity. Biol Reprod. 93(4):100. doi: 10.1095/biolreprod.115.128868. Epub 2015 Sep 9.
- Oguejiofor CF, Cheng Z, Abudureyimu A, Anstaett OL, Brownlie J, Fouladi-Nashta AA, Wathes DC. (2015) Global Transcriptomic Profiling of Bovine Endometrial Immune Response In Vitro. II. Effect of Bovine Viral Diarrhea Virus on the Endometrial Response to Lipopolysaccharide. Biol Reprod. 93(4):101. doi: 10.1095/biolreprod.115.128876. Epub 2015 Sep 9.
- Mohey-Elsaeed O, Marei WF, Fouladi-Nashta AA, El-Saba AA. (2015) Histochemical structure and immunolocalisation of the hyaluronan system in the dromedary oviduct. Reprod Fertil Dev. doi: 10.1071/RD14187. [Epub ahead of print]
- Chavoshinejad R, Marei WF, Hartshorne GM, Fouladi-Nashta AA. (2014) Localisation and endocrine control of hyaluronan synthase (HAS) 2, HAS3 and CD44 expression in sheep granulosa cells. Reprod Fertil Dev. doi: 10.1071/RD14294. [Epub ahead of print]
- Ghaffarilaleh V, Fouladi-Nashta A, Paramio MT. (2014) Effect of α-linolenic acid on oocyte maturation and embryo development of prepubertal sheep oocytes. Theriogenology. 82:686-96.
- Marei WF, Abayasekara DR, Wathes DC, Fouladi-Nashta AA.( 2014) Role of PTGS2-generated PGE2 during gonadotrophin-induced bovine oocyte maturation and cumulus cell expansion. Reprod Biomed Online. 28:388-400.
- Raheem KA and Fouladi-Nashta AA. (2014) Isolation and characterization of endometrial luminal epithelial and stromal cells in vitro. Sokoto J Vet Sci, 12:1-8.
- Salavati M, Ghafari F, Zhang T, Fouladi-Nashta AA. (2013) Influence of caffeine pretreatment on biphasic in vitro maturation of dog oocytes. Theriogenology 80:784-92.
- Wathes DC, Cheng Z, Marei WF, and Fouladi-Nashta AA (2013) Polyunsaturated fatty acids and fertility in female mammals: an update. CAB reviews 2013 8, N0. 041. doi: 10.1079/PAVSNNR20138041
- Raheem KA, Marei WF, Mifsud K, Khalid M, Wathes DC, Fouladi-Nashta AA. (2013) Regulation of the hyaluronan system in ovine endometrium by ovarian steroids. Reproduction. 145:491-504.
- Marei WF, Salavati M, Fouladi-Nashta AA (2013) Critical role of hyaluronidase-2 during preimplantation embryo development. Mol Hum Reprod. 19:590-9.
- Swangchan-Uthai T, Chen Q, Kirton SE, Fenwick MA, Cheng Z, Patton J, Fouladi-Nashta AA, Wathes DC. (2013) Influence of energy balance on the antimicrobial peptides S100A8 and S100A9 in the endometrium of the post-partum dairy cow. Reproduction 145:527-39.
- Swangchan-Uthai T., Lavender C.R., Cheng Z., Fouladi-Nashta A.A., Wathes D.C. (2012) Time Course of Defense Mechanisms in Bovine Endometrium in Response to Lipopolysaccharide. Biol Reprod. 87:135, 1–13
- Dirandeh E, Towhidi A, Zeinoaldini S, Ganjkhanlou M, Ansari Pirsaraei Z, Fouladi-Nashta A. (2013) Effects of different polyunsaturated fatty acid supplementations during the postpartum periods of early lactating dairy cows on milk yield, metabolic responses, and reproductive performances. J Anim Sci. 91:713-21.
- Salavati M., Ghafari F., Zhang T., Fouladi-Nashta A.A. (2012) Effects of oxygen concentration on in vitro maturation of canine oocytes in a chemically defined serum free media. Reproduction 144: 547-56.
- Marei W.F., Ghafari F., Fouladi-Nashta A.A. (2012) Role of hyaluronic acid in maturation and further early embryo development of bovine oocytes. Theriogenology 78: 670-7.
- Marei W.F., Wathes D.C., Fouladi-Nashta A.A. (2012) Differential effects of linoleic and alpha-linolenic fatty acids on spatial and temporal mitochondrial distribution and activity in bovine oocytes, Reproduction Fertility and Development 24: 679-90.
- Marei WF, Wathes DC, Fouladi-Nashta AA (2011) Differential effects of linoleic and alpha-linolenic fatty acids on spatial and temporal mitochondrial distribution and activity in bovine oocytes. Reproduction Fertility and Development 24: 679–690.
- Marei W.F., Wathes D.C., Fouladi-Nashta A.A. (2010) Impact of linoleic acid on bovine oocyte maturation and embryo development. Reproduction 139: 979-988.
- MAREI, W.F., WATHES, D.C. & FOULADI-NASHT, A.A. (2009) The effect of linolenic Acid on bovine oocyte maturation and development. Reproduction. 138: 771-81. PubMed ID: 19633135
- FOULADI-NASHTA, A.A.,WONNACOTT, K.E., GUTIERREZ, C.G, GONG, J.G., SINCLAIR, K.D., GARNSWORTH, P.C. & WEBB, R. (2009) Oocyte quality in lactating dairy cows fed on high levels of n-3 and n-6 fatty acids. Reproduction 138, 771-81. PubMed ID: 19633135
- GARNSWORTHY, P.C., FOULADI-NASHTA, A.A., MANN, GE., SINCLAIR, K.D. & WEBB, R. (2009) Effect of dietary-induced changes in plasma insulin concentrations during the early post partum period on pregnancy rate in dairy cows. Reproduction. 137, 759-68. PubMed ID: 19129370.
- Garnsworthy P.C., Fouladi-Nashta A.A., Mann G.E., et al.(2008) How does nutrition interact with fertility in dairy cows? Cattle Practice 16: 20-23.
- FOULADI-NASHTA, A. A., MOHAMET, L., HEATH, J. K. & KIMBER, S. J. (2008) Interleukin 1 signaling is regulated by leukemia inhibitory factor (LIF) and is aberrant in Lif-/- mouse uterus. Biol Reprod 79, 142-153. PubMed ID 18337516
- FOULADI-NASHTA, A. A., GUTIERREZ, C. G., GONG, J. G., GARNSWORTHY, P. C. & WEBB, R. (2007) Impact of dietary fatty acids on oocyte quality and development in lactating dairy cows. Biol Reprod 77, 9-17. PubMed ID 17344470
- Webb R., Dugan K., Quinn R.L., Fouladi-Nashta A.A. and Hunter M.G. (2006) Follicular development in mono-ovulatory and poly-ovular species: from fetus to fertilization. Acta Scientiae Veterinariae, 34 (Suppl 1): 95-114.
- SINGH, R., FOULADI-NASHTA, A. A., LI, D., HALLIDAY, N., BARRETT, D. A. & SINCLAIR, K. D. (2006) Methotrexate induced differentiation in colon cancer cells is primarily due to purine deprivation. J Cell Biochem 99, 146-155. PubMed ID 16598758
- FOULADI-NASHTA, A. A. & CAMPBELL, K. H. (2006) Dissociation of oocyte nuclear and cytoplasmic maturation by the addition of insulin in cultured bovine antral follicles. Reproduction 131, 449-460. PubMed ID 16514188
- NICHOLAS, B., ALBERIO, R., FOULADI-NASHTA, A. A. & WEBB, R. (2005) Relationship between low-molecular-weight insulin-like growth factor-binding proteins, caspase-3 activity, and oocyte quality. Biol Reprod 72, 796-804. PubMed ID 15564596.
- Kimber S.J., Fouladi-Nashta A.A, Mohamet L., Jones C.J.P., Schofield G. (2005). To implant or not to implant: the role of Leukaemia Inhibitory factor (LIF). In Critchley H, Cameron I and Smith S. Implantation and Early Development185-202, Proceedings of Royal College of Obstericians and Gynaecologists, London, UK.
- FOULADI-NASHTA, A. A., JONES, C. J., NIJJAR, N., MOHAMET, L., SMITH, A., CHAMBERS, I. & KIMBER, S. J. (2005) Characterization of the uterine phenotype during the peri-implantation period for LIF-null, MF1 strain mice. Dev Biol 281, 1-21. PubMed ID 15848385
- FOULADI-NASHTA, A. A., ALBERIO, R., KAFI, M., NICHOLAS, B., CAMPBELL, K. H. & WEBB, R. (2005) Differential staining combined with TUNEL labelling to detect apoptosis in preimplantation bovine embryos. Reprod Biomed Online 10, 497-502. PubMed ID 15901458
- FOULADI NASHTA, A. A., ANDREU, C. V., NIJJAR, N., HEATH, J. K. & KIMBER, S. J. (2004) Role of leukemia inhibitor factor (LIF) in decidualisation of murine uterine stromal cells in vitro. J Endocrinol 181, 477-492. PubMed ID 15171696
Chapters in textbooks
Mandana Beigi Boroujeni, Seyyed Amir Yasin Ahmadi , Ali Fouladi Nashta and Fataneh Ghafari (2023) An Introduction to the Use of Embryology in Clinical Practice. Frontiers in Stem Cell and Regenerative Medicine Research, 2023, Vol. 11, Chapter 12, Pages 1-10.
Papers in conferences
- Shattock A, Ghafari F, Piercy R, Fouladi-Nashta AA (2025) Establishment of an oviductal explant co-culture system to improve oocyte maturation success in dogs. Accepted for oral presentation in Fertility 2025 in Liverpool.
- Shattock A, Ghafari F, Piercy R, Fouladi-Nashta AA (2025) Confirmation of an immunological sperm sexing method for use in bulls. ccepted for oral presentation in Fertility 2025 in Liverpool.
- Qurat ul Ain, McCarthy A, Niakan K, Fouladi-Nashta AA (2025) Validation of sgRNAs to target GATA3 genes in bovine cell lines using CRISPR/Cas9 gene editing. Accepted for oral presentation in Fertility 2025 in Liverpool.
- Korchi M, Shattock A, Ghafari F Fouladi-Nashta AA (2025) Impact of ageing on hyaluronan production and ECM composition of ovaries. Accepted for oral presentation in Fertility 2025 in Liverpool.
- Fouladi-Nashta AA, Korchi M, Shattock A, Marei WFA, Ghafari F (2024) Age related decline in oocyte hyaluronan; impact on oocyte maturation and embryo development. AETE 2024, Brescia Italy. Rafid Fire oral presentation.
- Fouladi-Nashta AA, Ghafari F, Gutierrez CG, Maalouf WE, Marei WF, Tremaine T (2024) Studies on The Impact of Hyaluronidases and Low Molecular Weight Hyaluronan on Preimplantation Embryo Development, Morphokinetics, Pregnancy and Live birth rates in Sheep. SSR annual meeting, 16-20 July 2024, Dublin. (oral presentation)
- Maalouf WE, Jayasinghe SN, Ghafari F, Werling N, Fouladi-Nashta AA (2024) Bio-electrosprayed mammalian sperm remain viable. SSR annual meeting, 16-20 July 2024, Dublin.
- Shattock A, Piercy R, Fouladi-Nashta AA (2023) Toll-like receptor 7 (TLR7) expression is localized to the equatorial region of the sperm head in dogs, cows and sheep. European Association of Embryo Transfer Conference (AETE), Greece, September 2023.
- Ghafari F, Piercy R, Fouladi-Nashta AA (2023) Beneficial effects of melatonin on canine oocyte nuclear maturation through reduction of oxidative stress. European Association of Embryo Transfer Conference (AETE), Greece, September 2023.
- Oladipupo A, Fouladi-Nashta AA (2023) Investigating the roles of interferon tau stimulated genes in sheep embryo implantation. European Association of Embryo Transfer Conference (AETE), Greece, September 2023.
- Embegbu E, Ikechukwu O, Childs A, Fouladi-Nashta AA (2020) Ovarian histomorphometry and follicular development in pre-pubertal albino rats with dietary vitamin D supplementation. Fertility 2020 Conference on 8-11 January Edinburgh, UK.
- Mbegbu EC, Salavati M, Obidike IR, Childs AJ, Fouladi-Nashta AA (2019) Pattern of anti-mullerian hormone and vitamin D receptor expression at different phases of oestrous cycle in sheep ovaries. Fertility 2019 Conference on 3-5 January Birmingham, UK.
- Fouladi-Nashta AA, Ghafari F; Gutierrez, CG; Hartshorne, G. (2018) Impact of VLWHA on sheep blastocyst formation in vitro, viability after cryopreservation and pregnancy rate after embryo transfer) in Fertility 2018 conference in Liverpool (3-6 January 2018). Fertility 2018 Conference on 2-5 January Liverpool, UK.
- Mbegbu EC, Salavati M, Obidike IR, Childs AJ, Fouladi-Nashta AA (2018) Maternal Vitamin D Status Influences Anti-Mullerian Hormone Expression and Germ Cells Reserve in Sheep Foetal Ovaries. Fertility 2018 Conference on 2-5 January Liverpool, UK.
- Tremaine T, Wathes DC, Khalid M, Fouladi-Nashta AA (2015) A potential co-culture system of ovine blastocyst with uterine endometrium to mimic initial attachment of embryo implantation. Oral presentation, SRF annual congress, Oxford UK.
- Raheem, KA & Fouladi-Nashta AA (2015) Effect of hyaluronan on some molecular markers of implantation in sheep endometrial cells in vitro. Poster presentation, SRF annual congress, Oxford UK.
- Fouladi-Nashta AA, Forbes J, Yuen WC, Lock Man J, Green L. (2015). Impact of vitamin D on folliculogenesis in foetal ovaries and in vitro oocyte maturation and development. Oral presentation, Epiconcept annual meeting, Crete, Greece.
- Tremaine T, Salavati M, Bartens MC, Fouladi-Nashta AA (2015). Impact of zinc oxide treatment on in vitro maturation of canine oocytes. Poster presentation, Epiconcept annual meeting, Crete, Greece.
- Fouladi-Nashta, A.A.; Salavati, M.; Marei, W.F. (2013) Developmental pattern of hyaluronan system and its critical role during preimplantation embryo development. Oral presentation, SRF Annual Congress 9-11 July, Cambridge.
- Fouladi-Nashta, A.A. and WF Marei (2013) Is hyaluronan essential for embryo implantation? Lesson from studies in sheep. (Oral presentation, ESHRE meeting, London).
- Fouladi-Nashta, A.A. (2013) Critical role of hyaluronan system in pre-implantation embryo development and establishment of pregnancy. Oral presentation, Royan Congress 4-7 Sept, Tehran.
- Chavoshinejad, R.; Hartshorne, GM.; Marei, W.; Fouladi-Nashta, AA. (2013) Regulation of hyaluronan (HA) system in ovine granulosa cells cultured in vitro. ESHRE meeting 6-9 July, London.
- Marei, W.F. and Fouladi-Nashta, A.A. (2013) Hyaluronan degradation is required for optimal embryo development. AETE meeting 6-8 Sept, Istanbul, Turkey.
- Kabir A.R.; Wathes, D.C.; Fouladi-Nashta, A.A. (2013) Influence of steroids on expression of Hyaluronan and its related genes in sheep endometrial cell culture. SRF Annual Congress 9-11 July, Cambridge.
- Ghaffarilaleh, V.; Paramio, M.T.; Fouladi-Nashta, A.A. (2013) The effects of omega-3 and omega-6 polyunsaturated fatty acids on lamb embryo development and quality in entirely serum free media. Oral presentation, AETE meeting 6-8 Sept Istanbul, Turkey.
- Tremaine, T.; Fouladi-Nashta, A.A.; Khalid, M.; Wathes, D.C. (2013) Steroid regulation of gene and protein expression of osteopontin and [alpha] v [beta] 3 integrin in ovine endometrium. Endocrine Abstracts (2013) 31 P298
- Ghaffarilaleh, V.; Ghafari F.; Paramio M.T.; Fouladi-Nashta A.A. (2013) Effect of different concentrations and molecular weight of hyaluronic acid on survival of in vitro sheep embryos after cryopreservation. XV Jornadas sobre Producción Animal, Zaragoza 14 y 15 de mayo de 2013., 365-367
- Marei WF., Wathes DC., Abayasekara DRE., Fouladi-Nashta AA. Role of COX-2 related PGE2 and EP2 receptors during bovine oocyte maturation. European Society of Animal Reproduction, August 2012, Dublin.
- Raheem KA, Marei WF, Mifsud K, Wathes D.C., Fouladi-Nashta AA. 2012, Influence of ovarian steroid hormones on expression of hyaluronan and its associated genes and receptor in ovine uterus. Annual conference of the society of reproduction and fertility (SRF), Edinburgh, UK.
- Marei WF., Abayasekara DRE., Fouladi-Nashta AA. Does gonadotrophin-induced bovine oocyte maturation require cyclooxygenase-2 (COX2)? Presented in Society for Reproduction and Fertility annual conference, Edinburgh, 9-11 July 2012.
- Tremaine T., Khalid M., Wathes DC., Fouladi-Nashta AA. Expression and steroids regulation of OPN and αvβ3 integrin and angiogenic factors in sheep uterus. Presented in Society for Reproduction and Fertility annual conference, Edinburgh, 9-11 July 2012.
- Chavoshinejad R., Marei WF., Hartshorne., Fouladi-Nashta AA. Investigation of steroidogenesis by sheep granulosa cells in serum-free culture system. Presented in Society for Reproduction and Fertility annual conference, Edinburgh, 9-11 July 2012.
- Wathes DC., Cheng Z., Fenwick MA., Swangchan-Uthai T., Wang Z-g., Marei W., Fouladi-Nashta AA. 2012, Retinoid signaling pathways in the bovine oviduct. Annual conference of the society of reproduction and fertility (SRF), Edinburgh, UK.
- Ghaffari-Laleh V., Marei WF., Ghafari, F., Zhang T., Fouladi-Nashta AA. Effects of different sizes of HA on development of sheep embryos and blastocyst survival after vitrification. Presented in Society for Reproduction and Fertility annual conference, Edinburgh, 9-11 July 2012.
- Swangchan-Uthai T., Chen Q., Kirton S.E., Cheng Z., Fouladi-Nashta AA. Wathes DC. Endometrial expression of the antimicrobial peptides S100A8 and S100A9 indicate a role in innate immunity of the postpartum dairy cow. Presented in Society for Reproduction and Fertility annual conference, Edinburgh, 9-11 July 2012.
- AA Fouladi-Nashta, DC Wathes, WF Marei (2011) Diverse effects of polyunsaturated fatty acids on oocyte maturation and development in vitro. Royan International Twin Congress, 7-9 Sept, Tehran, Iran. (oral presentation).
- WF Marei and AA Fouladi-Nashta (2011) Size specific effects of hyloronan (HA) on sheep blastocyst formation and quality in vivo. 44th SSR annual meeting, 31July-3rd August, Oregon, USA.
- KA Raheem, WF Marei, DC Wathes, AA Foluadi-Nashta (2011) Progesterone Regulation of Hyaluronan Synthesis in Sheep Uterus. SSR annual conference, Brighton, UK.
- R Chavoshinejad, GM Hartshorne, WF Marei, AA Fouladi-Nashta (2011) Steroid hormones regulation of hyaluronan synthesis in sheep ovaries. SSR annual conference, Brighton, UK.
- M Salavati, F Ghafari, T Zhang, AA Fouladi-Nashta (2011) Effects of caffeine on in vitro maturation of dog oocytes. SSR annual conference, Brighton, UK.
- AA Fouladi-Nashta, WF Marei (2011) Small hyaluronan fragments mediate oocyte nuclear maturation and improve preimplantation embryo development in ruminants. (AETE Conference, 9-11 September, Chester, UK)
- AA Fouladi-Nashta, W F Marei (2011) Hyaluronidaze affects oocyte maturation and supports preimplantation embryo development (Second World Congress in Reproductive Biology, 7-9 October 2011, Cairns, Australia).
- Fouladi-Nashta, AA; Marei W.F; Ghaffari F. (2010) Small size hyluronan promotes bovine oocyte maturation and embryo development in vitro. SSR meeting, Milwaukee, Wiscounsin, USA, Abst. 247.
- Marei, WF; Bayram, H; Wathes, DC; Abayasekara, DRE; Fouladi-Nashta, A.A. (2010) Prostaglandin E2 partially mediates gonadotrophin-dependent bovine oocyte maturation. SSR meeting, Sutton Bonington, University of Nottingham. Abst. 32.
- Marei W.F., Wathes D.C., Fouladi-Nashta A.A. (2009) Mitochondrial distribution in PUFA treated bovine oocytes. Society for Reproduction and Fertility annual meeting, Oxford, July 2009.
- Swangchan-Uthai T., Cheng Z., Fouladi-Nashta A.A., Wathes D.C. (2009) Effects of lipopolysaccharide (LPS) on gene expression in bovine endometrium. Society for Reproduction and Fertility annual meeting, Oxford, July 2009.
- Fouladi-Nashta AA; Gutierrez, CG; Sinclair, KD; Garnsworthy, PC; Webb, R (2008) Sources of dietary fatty acids affect the developmental potential of oocytes and quality of embryos in lactating dairy cows. ICAR conference, Budapest, Hungry.
- Marei W.F., Wathes D.C., Fouladi-Nashta A.A. (2008) Linoleic acid affects nuclear maturation and cAMP content of bovine oocytes. SRF conference, Edinburgh.
- Marei W.F., Wathes D.C., Fouladi-Nashta A.A. (2007) The effect of linoleic acid on bovine oocyte maturation in vitro. Presented in International Conference in Farm Animal Reproduction, Roldoc, Netherland.
- A.A. Fouladi-Nashta, K. J. Dugan, R. Webb (2005) Immunohistochemical localisation of BMP receptors in bovine foetal ovaries. Abstract 72, Fertility 2005, Warwick University, UK.
- Fouladi-Nashta, A.A., Gutierrez, C.G., Garnsworthy, P. C. and Webb R. (2005). Effects of dietary carbohydrates on oocyte /embryo quality and development in high yielding lactating dairy cattle. Abstract 244, SSR annual meeting, Quebec City, Canada. Times Cited: 8
- Singh R., Fouladi-Nashta A.A., Sinclair, KD (2005). Purine biosynthesis in Methotroxide induced differentiation in colon cancer cell. National Cancer Research Institute, 2-4 Oct 2005, Birmingham, UK.
- Fouladi-Nashta, A.A., Alberio, R., Nicholas, B., Campbell, K.H.S. and Webb, R. (2004). A simple and fast method for concurrent differential staining and TUNEL labeling of bovine blastocysts. Reproduction Fertility and Development 16:1-2, Abstract 150.
- Fouladi-Nashta, A.A., Gutierrez, C.G., Russell, H.F., Garnsworthy, P.C. and Webb R. (2004) Effects of dietary fatty acids on oocyte quality and development in lactating dairy cows. Biology of Reproduction, Abstract 62, SSR annual meeting, Vancouver, Ca.
- Mohamet, L, Fouladi-Nashta, A.A, Nijjar, N., Smith, A. and Kimber, SJ. (2004) Regulation of uterine gene expression by leukemia inhibitory factor. Biology of Reproduction, Abstract 249, SSR annual meeting, Vancouver, Ca.
- Nicholas B., Alberio R., Fouladi-Nashta A.A. and Webb R. (2004) Insulin-like growth factor binding proteins as predictive markers for developmentally competent oocytes. Biology of Reproduction, Abstract 56, SSR annual meeting, August 2004, Vancouver, Ca. (I did oral presentation in this meeting).
- Fouladi Nashta, A.A, Schofield, G., Andreu, C.V., Nijjar, N., Smith, A.G. Heath, J.K. and Kimber, S.J (2002) Cell biology of embryo-implantation: unravelling the role of leukaemia inhibitory factor Endocrine Abstracts 4: S18.
- Fouladi-Nashta, A.A., Nijjar, N. and Kimber, S.J. (2002). Immunohistochemical studies on markers associated with early pregnancy and decidualisation in LIF KO mouse uterus. Gordon Conference, Reproductive Tract Biology, Conneticut, USA.
- Fouladi-Nashta, A.A. and. Campbell, K. H. S. (1999). Addition of insulin to bovine antral follicles in vitro induces ultrastructural and protein profile changes characteristics of mature oocytes. Theriogenology 51: Abstract. 372.
- Fouladi-Nashta, A.A., MacFarlane, S. and Campbell, K.H.S. (1997). Effects of Colony Stimulating Factor on bovine preimplantation embryo development in vitro. Theriogenology, 1997 (17), Abst. 333.
- Fouladi-Nasgta A.A and Bazargani T. (1988) An investigation on serum magnesium changes in dairy herds around Tehran in relation to: seasons, age and different parturient groups. Scientific Journal of Faculty of Veterinary Medicine, Tehran University.
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2007- present |
I give many Lectures in animal reproduction to BVetMed, BioVeterinary Science, Graduate Accelerated BVetMed students |
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2007- present |
Practical teaching anatomy and histology in dissection room and taching lab to BVetMed and GAB courses |
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2007- present |
Directed Learning to BVetMed1, 2 and GAB students |
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2007- present |
ISF oral examiner for BVetMed1, BVetMed2 and GT students |
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2014-present |
Lectures and practicals and DL for BSc3 ACIR module |
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2007- present |
Practical reproduction teaching to BSc1 and Gateway students |
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2007- present |
Supervisor for BSc3 students |
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2007- present |
Supervisor BVetMed RP2 projects |
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2007- present |
Supervisor and internal Examiner for BioVetSci year 1 Extended Essay, BVetMed2 CATR and research projects |
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2007-present |
PDP tutor for BVetMed1, 2 and GAB students |
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2020-2021 |
Leader of Integrated Concept- BVetMed2- Animal Breeding |
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2016-2020 |
Leader of BSc2 Resear Block- reproduction |
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April 2023- |
Breeding & Genetic Technologies - Animal Welfare Team at Defra, UK |
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2008-April 2024 |
External Examiner for PhD thesis at Sheffield University (UK), Edinburgh University (UK), University College Dublin (Ireland), University Autonomous of Barcelona (Spain), Uninversity of Galway (Ireland), Warwick University, Kent University, Leeds University, Nottingham University, University of London. |
Working with Industry:
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2021-present |
IVF Bioscience- member of advisory panel |
Professional Society Memberships
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Dates |
Society Membership |
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2011- present |
UK representative and a member of Standing Committee in International Congress in Animal Reproduction (ICAR) |
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2021-Jan 2025 |
Elected Chair of Grant and Membership Committee, and General Secretary of the Society for Reproduction and Fertility (SRF) |
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2018-2021 |
Elected Member of the SRF Council |
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2010-2013 |
Elected Member of the SRF Council and member of the SRF Programme Committee |
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2014-present |
Member of Association of European Embryo Transfer (AETE) |
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2010-2014 |
Society for Study of Reproduction (SSR), member of International Membership Subcommittee- UK representative |
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2012-2015 |
Member of Cost Action Epiconcept Consortium |
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2022- present |
Associate Editor, Frontiers in Veterinary Science - Animal Reproduction – Theriogenology |
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2020- present |
Associated Editor, Journal of Sustainable Veterinary and Allied Sciences |
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Varriable |
Reviewer for Reproduction, Animals, Theriogenology, Animal Reproduction Science and Reproduction Fertility and Development (RFD) jand International J of Medical Science ournals |
