Mrs Lexi Keene-Snickers
Department: Pathobiology & Population Sciences
Campus: Hawkshead
Lexi is a postdoc in the lab of Dr. Sarah Hill where she works on projects related to the Genomics for Animal and Plant Disease Center (GAP-DC2). She is primarily focused on the surveillance of viruses occurring in animals at the wild/domestic/agricultural interface to better prepare the UK for potential animal driven disease outbreaks.
Lexi obtained her Bachelor's of Science in Biomedical Science with a minor in Chemistry from Northern Arizona University in 2017. She then worked as a Research Assistant I at the Translational Genomics Research Institute, Pathogen and Microbiome Division. She primarily worked on biodefense and Mycobacterium tuberculosis projects centered around amplicon assay development for high throughput sequencing for the rapid detection of biothreat agents and their near neighbors or the detection of clinically relevant SNPs. During the Covid-19 pandemic she worked in the clinical lab processing potential SARS-CoV2 positive specimens for surveillance in under served communities in rural Arizona. She graduated from Colorado State University in the summer of 2025 with a PhD in Cell & Molecular Biology and graduate certificate in Data Analysis. Her PhD focused on the evolution of a persistent viral infection of Drosophila melanogaster called galbut virus. In this work she established the use of old, dried insect museum specimens as a source of viral RNA to study virus evolution.
Lexi was an NIH T32 Fellow from 2021-2023. She was alao received two awards for her mentorship skills and obtained an award for mentorship training that provided funding for an undergraduate researhcer. She has won several awards for scientific talks and posters presentations and successfully secured funding for attendance at several conferences during her PhD.
Keene-Snickers A.H., Brehm A.L., Dunham T.J., Gelpi T., and Stenglein M.D. Constrained Reassortment and Genotype-Specific Traits Shape the Evolutionary Landscape of Galbut Virus. Accepted (Virus Evolution).
Keene-Snickers, A. H., Dunham, T. J., & Stenglein, M. D. Experimental assessment of 3D-printed traps and chemical attractants for the collection of wild Drosophila melanogaster. Fly 2025, 19(1). https://doi.org/10.1080/19336934.2025.2502184
Cross, S.T., Brehm, A.L., Dunham, T.J., Rodgers, C.P., Keene, A.H., Borlee, G.I. & Stenglein, M.D. Galbut Virus Infection Minimally Influences Drosophila melanogaster Fitness Traits in a Strain and Sex-Dependent Manner. Viruses 2023, 15, 539. https://doi.org/10.3390/v15020539
Broz A, Keene AH, Gyorfy MF, Hodous M, Johnson IG & Daniel B. Sloan, Sorting of plant mitochondrial and plastid heteroplasmy is extremely rapid and depends on MSH1 activity, Proc Natl Acad Sci USA, 2022. https://doi.org/10.1073/pnas.2206973119
Ratnayake, O.C.; Gendler, P.; Swartzwelter, B.; Keene, A.; Brehm, A.L.; Quackenbush, S.L.; Rovnak, J.; Perera, R. The 22nd Annual Meeting of the Rocky Mountain Virology Association. Viruses 2023, 15, 98. https://doi.org/10.3390/v15010098
