Department: Clinical Science and Services
Lawson, J.S., Jepson, R.E. (2021) Feline comorbidities: The intermingled relationship between chronic kidney disease and hypertension, Journal of Feline Medicine and Surgery 23 (9), 812-822
Lawson, J.S., Syme, H.M., Wheeler-Jones, C.P.D., Elliott, J. (2021) Investigation of the transforming growth factor-beta 1 signalling pathway as a possible link between hyperphosphataemia and renal fibrosis in feline chronic kidney disease, The Veterinary Journal 267, 105582
Lawson, J.S., Syme, H.M., Wheeler-Jones, C.P.D., Elliott, J. (2019) Characterisation of Crandell-Rees Feline Kidney (CRFK) cells as mesenchymal in phenotype. Research in veterinary science 127, 99-102.
Lawson, J.S., Syme, H.M., Wheeler-Jones, C.P.D., Elliott, J. (2018) Characterisation of feline renal cortical fibroblast cultures and their transcriptional response to transforming growth factor beta 1.
BMC Veterinary Research, 14; 76.
Lawson, J.S., Liu, H.H., Syme, H.M., Purcell, R., Wheeler-Jones, C.P.D., Elliott, J. (2018) The cat as a naturally occurring model of renal interstitial fibrosis: Characterisation of primary feline proximal tubular epithelial cells and comparative pro-fibrotic effects of TGF-β1. PLoS One 13 (8), e0202577
Lawson, J.S., Syme, H.M., Wheeler-Jones, C.P.D., Elliott, J. (2016) Urinary active transforming growth factor β in feline chronic kidney disease. The Veterinary Journal 214, 1-6
Lawson, J.S., Elliott, J., Wheeler-Jones, C.P.D., Syme, H.M., Jepson, R.E. (2015) Renal fibrosis in feline chronic kidney disease: known mediators and mechanisms of injury. The Veterinary Journal 203 (1), 18-26
Kidneys filter the blood and produce urine and so problems with kidney function can result in a variety of health problems for a cat. Chronic kidney disease (CKD) is the persistent loss of kidney function over a period of time. CKD is the most common kidney disease affecting cats as they get older. The RVC’s Geriatric Cat Clinic was established in 1992 with the aim of researching the common conditions of older cats and to help with the care and medical management of the cats that attend the clinic.