Autoimmune conditions (e.g. Systemic Lupus Erythematosis, Discoid
Lupus Erythematosis, Autoimmune Haemolytic Anaemia)
Metabolic diseases (e.g. diabetes mellitus, chronic renal failure
and secondary renal hyperparathyroidism)
Immuno-suppressive viruses (e.g. FIV and FeLV).
Domestic pets are substantially less demonstrative of oral pain
than humans. Therefore the owner may be unaware of major lesions
until the disease is well advanced or until more obvious signs,
such as a discharge, swelling, or severe halitosis, are present.