Biology has become increasingly quantitative in the past 20 years. Collaborations among mathematicians, statisticians, computer scientists and biologists are becoming an essential part of modern biological sciences.
With massive amounts of data generated daily, we are pressed to develop theoretical frameworks for interpreting information and using it to solve applied problems. At the RVC we are striving to encourage collaboration among researchers in various quantitative fields to advance our understanding of biology.
The RVC Veterinary Epidemiology, Economics and Public Health Group has strong methodological expertise in risk analysis, spatial analysis, social network analysis, animal health economics, etc. We also have the international renowned the Centre for Animal Welfare that adopts an interdisciplinary approach to answering fundamental questions about how animals perceive and process information about their world and the implications of this for their management, as well as tackling the science and application of welfare assessment. The research team at the Structure and Motion Laboratory includes biologists, engineers and computer scientists to study locomotion, social behaviour, gait analysis, etc.
In addition to these established research centres, RVC has also strong expertise in bioinformatics, statistics, comparative genomics, and image processing and analysis.
Academic specialists in the quantitative disciplines mentioned above include:
- Dr Denis Larkin is an expert in comparative genomics, and is interested in Comparative Mammalian Genomics, Chromosome Analysis, and Evolution. Dr Larkin holds several BBSRC funded research projects and is the primary researcher for the Evolution Highway website that provides a visual means for simultaneously comparing genomes of multiple amniote species.
- Dr Michael Doube in the Comparative Biomedical Sciences department is specialised in imaging musculoskeletal tissues, and processing of those images. Dr Doube is an active member of the ImageJ community, and maintains the BoneJ user and developer group.
- Dr Ruby Chang, a Chartered Statistician, provides basic and advanced statistical training and consultancy for research and academics staff and postgraduate students. She also provides external training and consultancy regarding statistical data analysis, study design and sampling strategies.
- Dr Andrew Hibbert manages the RVC microscopy unit, the Imaging Suite, which contains a wide range of solutions for the quantitative analysis of microscopical images. He advises on routine uses of these software and provides bespoke analysis programs as required for our more advanced or challenging projects.
- Dr Dong Xia works with integrate data sets generated from multiple omics platforms with systems modelling. His research focuses on understanding the molecular mechanisms of host-pathogen interactions using high-resolution approaches coupled to bioinformatics and machine learning approaches.
The RVC is also part of the UCL led BBSRC funded Doctoral Training Partnership (www.lido-dtp.ac.uk) where the emphasis is on training in mathematical biology.
RVC Quantitative Biology Resources Contacts
- Bone image processing and analysis
Michael Doube firstname.lastname@example.org
- PK/PD modelling
Ludovic Pelligand email@example.com
- Quantitative genetics / Genomic
Denis Larkin firstname.lastname@example.org
- Statistics / Statistical genetics
Ruby Chang email@example.com
- Behaviour analysis
Charlie Burn firstname.lastname@example.org
Siobhan Abeyesinghe email@example.com
— Centre for Animal Welfare
- Epidemiology & Social network
Julian Drewe firstname.lastname@example.org
— Veterinary Epidemiology, Economics and Public Health Group
- Mathematical modelling / Computer simulation
Guillaume Fournie email@example.com
- Locomotion and gait analysis
— Structure and Motion Laboratory
- Multi-Omics data analysis
Dong Xia firstname.lastname@example.org