People: Sarah Finnegan, Rowena Packer, Holger Volk, Monica Daley

Epilepsy is the most common chronic neurological brain disease and can be difficult to manage. Identification of prodromes (pre-seizure changes) may enable for new treatment avenues to be explored.  

Prodromes’ are long term changes in behaviour that occur before a seizure.  The ability to predict upcoming seizure activity may allow us to use anti-epileptic drugs in a ‘smart’ way, to allow us to intervene and try to stop the seizure occurring. Being able to predict when a seizure is likely to occur may improve quality of life of both you and your dog. For this we need to learn how to recognise prodromes in dogs with epilepsy.  

For this study, dogs will be recruited with idiopathic epilepsy and asked to wear a collar containing two accelerometer devices which detect activity for up to 21days. Owners will be asked to complete a seizure diary during the study period.  

Who can be involved?

We are recruiting ALL dogs of any breed, age, sex or neutered status from the United Kingdom. They must have been; diagnosed by a vet with bloods and urine tests to confirm idiopathic epilepsy, have a history of two or more seizures per month, no other concurrent diseases and have mainly generalised tonic-clonic activity.  

What is involved?

Owners will fill out a survey to ensure eligibility and to identify any prodromal and post ictal changes they may have observed. Eligible dogs will wear a special collar containing two activity monitors (accelerometers) for up to 21days. The collar will be sent and returned to your home address via pre-paid Royal Mail envelopes. Owners will be asked to complete a seizure diary during the study period.  

If you would like to take part in PREDICT, please fill out this questionnaire to let us know about your dog and we will be in touch: https://www.surveymonkey.co.uk/r/PREDICTstudy

If you would like further information about any aspect of the study please do not hesitate to ask, and contact Dr Sarah Finnegan via email on sfinnegan@rvc.ac.uk  

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