| Liam Good |
Using antisense agents as antibacterials to target sense messenger RNAs |
Alternative therapies |
| Andrew Rycroft |
Developing vaccines for bacterial diseases in pigs as alternatives to antimicrobials |
Alternative therapies |
| Andrew Rycroft |
Pharmacodynamics and resistance in Pasteurellaceae, primarily Mannheimia and Pasteurella |
Pathogenicity & resistance mechanisms |
| Andrew Rycroft |
Commercial lab-based studies on antimicrobial and antifungal action and resistance (particulary florfenicol) |
Pathogenicity & resistance mechanisms |
| Andrew Rycroft |
Recognising mechanisms of resistance in Pasteurellaceae |
Pathogenicity & resistance mechanisms |
| Andrew Rycroft |
Genome wide association methods to investigate pathogenicity, population structure and serovar in Haemophilus parasuis |
Pathogenicity & resistance mechanisms |
| Andrew Rycroft |
Resistance in Mycoplasma hyopneumoniae isolates from three European countries |
Epidemiology, surveillance & economics |
| Andrew Rycroft |
Species structure of Mycoplasma hyopneumoniae |
|
| Sharon Kendall |
Identfication of novel antimicrobial resistance targets in zoonotic Mycobacteria using whole genome essentiality screening |
Pathogenicity & resistance mechanisms |
| Sharon Kendall |
Using CRISPRi for the verification of novel antimicrobial resistacne targets in zoonotic Mycobacteria |
Pathogenicity & resistance mechanisms |
| Mandy Nevel |
Alternatives to zinc in pig production, Kings College London, pig industry |
Alternative therapies |
| Richard Kock |
UCL, LSHTM (Biocor funding) |
|
| Anette Loeffler |
Exchange of AMR elements between humans and dogs, |
Pathogenicity & resistance mechanisms |
| Anette Loeffler |
Antimicrobial resistance in staphylococci amongst UK wildlife (squirrels, foxes, bats) |
Epidemiology, surveillance & economics |
| Anette Loeffler & Ross Bond |
PhD student on topical therapy alternatives to systemic therapies in canine pyoderma (fusidic acid, chlorhexidine, gene transfer in S. aureus) |
Alternative therapies |
| Ludovic Pelligand & Andrew Rycroft |
Hollow fibre system for simulating drug ingress and egress from tissues and antimicrobial drug concentrations, UCL/VMD |
Alternative therapies |
| Ludovic Pelligand & Peter Lees |
Vetcast – a European group that defines clinical breakpoints (using MIC data, doses and population pharmacokinetic of antimicrobial drugs) |
|
| Ana Mateus |
FAO review on AMR epidemiology |
Epidemiology, surveillance & economics |
| Ana Mateus & Javier Guitian |
Systematic review on AMR in food at retail level (RVC, FSA funded) |
Epidemiology, surveillance & economics |
| Ana Mateus & Dave Brodbelt |
Investigation of extent of antimicrobial usage and risk factors in small animal first opinion practices (PhD) |
Antimicrobial usage |
| Ana Mateus |
Investigation of behaviors and beliefs of veterinarians influencing decision-making involved in the selection of antimicrobial therapy in companion animals (PhD) - K Staerk, D Brodbelt, A Mateus, N Barber, 2008-2010 |
Antimicrobial usage |
| Ana Mateus & Dave Brodbelt |
Investigation of antimicrobial usage in dogs and cats in first opinion veterinary practices in England using VetCompass (RVC, VMD funded) |
Antimicrobial usage |
| Ana Mateus |
Current British veterinary attitudes to the use of perioperative antimicrobials in small animal surgery |
Antimicrobial usage |
| Ana Mateus |
Public health risk of AMR transfer from companion animals |
Epidemiology, surveillance & economics |
| Ana Mateus |
Antibiotic use in companion animals: a mixed methods anthropological study (LSHTM/ RVC; Bloomsbury PhD) |
Antimicrobial usage |
| Ana Mateus |
How do policymaker perceptions of antimicrobial resistance drive behaviour and policies for appropriate antimicrobial use? A case study of Pakistan |
Antimicrobial usage |
| Javier Guitian & Ana Mateus |
Preproposal to EU H2020 led by Utrecth University and focused on AMU and AMR in pig farming in EU and China |
Antimicrobial usage |
| Javier Guitian & Ana Mateus |
Unsuccessful applicaton to JPIAMR to carry out work on AMR in pigs and pig farmers in several european countries |
Antimicrobial usage |
| Lucy Brunton |
Antimicrobial usage and feeding practices on UK dairy farms |
Antimicrobial usage |
| Lucy Brunton |
Epidemiology of ESBL E. coli on UK dairy farms |
Epidemiology, surveillance & economics |
| Kate Mellor, Stuart Reid |
Long term trends and patterns in AMR among bacterial isolates from multiple animal species over 20 years (LSHTM/RVC/Sanger/APHA PhD) |
Epidemiology, surveillance & economics |
| Katharina Staerk, Ana Mateus, Barbara Haesler, Houda Bennani |
Assessment of effectiveness of AMR strategy in the UK in human and veterinary medicine (LSHTM/RVC, funded by the Department of Health, UK) |
Epidemiology, surveillance & economics |
| Kevin Queenan, Barbara Haesler, Jonathan Rushton |
Review of Surveilance Systems and building a business case for a OH approach (FAO/RVC/LCIRAH); |
Epidemiology, surveillance & economics |
| Kevin Queenan, Jonathan Rushton |
Lit review of veterinary Antibiotic usage in livestock and aquaculture in Africa (OIE/WB); Uganda case study for Rapid assessment of antimicrobial use in animals and antimicrobial resistance in low and middle income countries - contribution to World Bank global report on the Economic Cost of Antimicrobial Resistance |
Antimicrobial usage |
| Barbara Haesler |
Integrated surveillance system evaluation for antimicrobial resistance at the human-animal interface (led by University of Montreal, Canada) |
Epidemiology, surveillance & economics |
| Houda Bennani, Barbara Haesler, Katharina Staerk |
Evaluating antimicrobial resistance surveillance in the United Kingdom from a one health perspective (PhD, LSHTM) |
Epidemiology, surveillance & economics |
| Steven van Winden, Liam Good |
Evaluating prevalence of AMR genotype in S aureus mastitis cases, and relating this with phenotypic and management variation. |
Epidemiology, surveillance & economics |
| Pablo Alarcon |
Evaluation of AMR scanning surveillance in England and Wales |
Epidemiology & surveillance |
| Pablo Alarcon |
Antimicrobial residues in dairy value chain in Kenya |
Epidemiology, economics |
| Camilla Strang, Lucy Brunton, Pablo Alarcon, Jackie Cardwell |
Antibiotic usage on dairy farms in GB: improving data capture and exploring drivers |
AMU, epidemiology, surveillance & economics |
| Lucy Brunton, Maria Garza, Barbara Haesler, Ana Mateus, Javier Guitian |
AMFORA: Applying a One Health systems modelling approach to formulate strategies for mitigating the risk to human health of antibiotic resistance in Aquaculture |
Epidemiology, surveillance & economics |
| Solomon Olorunleke, Lucy Brunton |
Molecular Analysis of the Prevalence of Antibiotics Resistance among Enterobactericeae in Food-Producing Animals and Humans in South-Eastern Nigeria |
Epidemiology & surveillance |
| Doaa Elkholy, Dave Brodbelt, Richard Booth, Lucy Brunton, Noel Kennedy, Ana Mateus, Dan O'Neil |
Antimicrobial usage in farm animal veterinary practice in the UK: A mixed methods approach (LSHTM) |
Antimicrobial usage |
| Maria Garza, Barbara Haesler, Lucy Brunton |
A typology of interventions to reduce antimicrobial usage in aquaculture |
Antimicrobial usage |
| Maria Garza, Lucy Brunton, Barbara Haesler |
Can better governance reduce antimicrobial usage? An assessment of Vietnamese aquaculture systems |
AMU, epidemiology, surveillance & economics |
| Liam Good |
Formulation of PHMB-based nanoparticles for targeted killing of zoonotic fungi (UCL, Blueberry Therapeutics) |
Alternative therapies |
| Ludovic Pelligand |
PK/PD-informed clinical breakpoint determination for colistin in chicken to limit emergence of resistance and improve One Health antimicrobial sustainability (LSHTM) |
Pathogenicity & resistance mechanisms |
| Barbara Haesler, Houda Bennani, Ana Mateus |
Convergence in evaluation frameworks for integrated surveillance of AMR |
Epidemiology, surveillance & economics |
| Anette Loeffler & Sian-Marie Frosini |
PET-Risk: Transmission of multidrug-resistant bacteria between pets and humans during different types of animal infection |
|
| Fiona Tomley, Ayona Silva-Fletcher, Guillaume Fournié, Barbara Häsler, Androniki Psifidi, Nicola Lewis, Damer Blake, Ludovic Pelligand, Dirk Pfeiffer and Oliver Pybus |
GCRF One Health Poultry Hub |
|
| Ben Swift |
Development of rapid diagnostics to detect AMR mycobacterial infections |
Pathogenicity & resistance mechanisms |
| Martin Walker, Joanne Webster |
A data sharing platform to improve treatment outcomes in neglected tropical diseases (funded by Wellcome with Infectious Disease Data Observatory, University of Oxford) |
Anthelmintic drug efficacy |
| Claire Heffernan |
Supporting Evidence-Based Policy: a longitudinal study of AMR risk behaviours among livestock keeping communities in India and Kenya |
Antimicrobial usage |
| Liam Good, Steven Van Winden |
Polyplex nanoparticle for mastitis control |
Alternative therapies |
| Liam Good |
Antimicrobial nanofibers |
Alternative therapies |
| Martin Walker, Joanne Webster |
A data sharing platform to improve treatment outcomes in neglected tropical diseases (funded by Wellcome with Infectious Disease Data Observatory, University of Oxford) |
Anthelmintic drug efficacy |
| Joanne Webster, Martin Walker, Barbara Heasler |
ZELS SR - CATTLES (2019-2021) where we are evaluating drug (praziquantel/PZQ) efficacy in livestock, together with facilitating access to veterinary-formula PZQ, implementing a T3 policy, and modelling resistance risk etc . This follows on from the recently finished BBSRC ZELS SHEEP (2015-2019)– where we evaluated PZQ efficacy in both humans and livestock across West Africa (PI myself) |
Anthelmintic (PZQ) drug efficacy, usage, resistance risk amongst livestock, modelling |
| Joanne Webster, Martin Walker, Elsa Leger |
Bloomsbury set (2019-2021) were we are evaluating and optimizing novel diagnostics to test of schistosomiasis in livestock and risk of emerging drug resistance |
Diagnostics, PZQ efficacy, social uptake, modelling |
| Joanne Webster, Martin Walker |
EDCTP FibroScHot (2018-2022) where we have an major component on the population genetics and genomics of PZQ efficacy |
PZQ efficacy, epidemology, genetics and genomics |
| Joanne Webster |
Wellcome Trust (2018-2022) Genomics of PZQ Resistance. This follows on from a recent MRC one on the genomics of PZQ Resistance, both in partnership with Sanger |
Genomics of PZQ-R |
| Joanne Webster |
WHO (2018-2019) Assessment of anthelminthic drug efficacy of single dose praziquantel against schistosomiasis (PI myself with partners in Belgium, and WHO of course, where I head the PZQ drug efficacy working group/expert advisor on NTD drug efficacy working group etc. |
Epidemiology and population genetics of PZQ-R |
| Joanne Webster |
NIH. (2016-2021) Genetic basis of PZQ-R (here I am Co-I, with PIs in the US. |
Genomics of PZQ-R |
