I am a BBSRC LIDo funded PhD student investigating the genetic architecture of hypertrophic cardiomyopathy (HCM) in cats, supervised by Dr Androniki Psifidi, Professor Virginia Luis Fuentes, Professor David Connolly (RVC) and Professor Perry Elliot (UCL).
HCM is strikingly similar in both cats and humans with a significant clinical heterogeneity making diagnosis challenging. This project aims to identify both genetic and environmental risk factors of HCM across cat breeds. Enhancing our understanding of HCM genetics will facilitate the development of targeted DNA tests in cats to enable disease control though selective breeding alongside identifying genetically susceptible individuals prior to clinical onset. Results of this work may also lead to the discovery of new drug targets for HCM.