I am Professor of Molecular Immunology. My current mainresearch interest is the ontogeny of the innate immune system between species, the importance of SNP in innate immune receptors for ligand binding, and how we can use our knowledge regarding the innate immune system to design new/optimise existing vaccine strategies.
I graduated from the University of Veterinary Medicine in Hannover (Germany) in 1991, and received a PhD (DrMedVet) in Virology at the University of Zuerich. This was followed by a Marie Curie Research Fellowship in the lab of Chris Howard at the Institute for Animal Health (IAH Compton, UK). During this time, I also passed the exam as Specialist Veterinarian (Fachtierarzt FVH) for Laboratory Medicine and Immunology in Switzerland and gained a Ph.D. in Immunology (University of London). I then moved back to the ETH Zuerich as a group leader and senior scientist, continuing the work started on bovine innate immune cells. In 2001, I was appointed as assistant professor (tenure track) at the Immunology Division at the Institute of Veterinary Virology (University of Bern) under Thomas Jungi, from where I moved to the RVC in 2003.
See Werling Lab - Innate Immune System for more information.
Published in 2013
1: Gibson AJ, Coffey TJ, Werling D. Of creatures great and small: the advantages
of farm animal models in immunology research. Front Immunol. 2013 May 27;4:124.
doi: 10.3389/fimmu.2013.00124. Print 2013. PubMed PMID: 23750160.
2: Schmitz S, Henrich M, Neiger R, Werling D, Allenspach K. Comparison of TNFα
responses induced by Toll-like receptor ligands and probiotic Enterococcus
faecium in whole blood and peripheral blood mononuclear cells of healthy dogs.
Vet Immunol Immunopathol. 2013 May 15;153(1-2):170-4. doi:
10.1016/j.vetimm.2013.02.014. Epub 2013 Feb 27. PubMed PMID: 23507437.
3: Offord V, Werling D. LRRfinder2.0: A webserver for the prediction of
leucine-rich repeats. Innate Immun. 2012 Nov 23. [Epub ahead of print] PubMed
4: Schmitz S, Hill S, Werling D, Allenspach K. Expression of trefoil factor genes
in the duodenum and colon of dogs with inflammatory bowel disease and healthy
dogs. Vet Immunol Immunopathol. 2013 Jan 15;151(1-2):168-72. doi:
10.1016/j.vetimm.2012.10.009. Epub 2012 Nov 2. PubMed PMID: 23177627.