I am Professor of Molecular Immunology. My current mainresearch interest is the ontogeny of the innate immune system between species, the importance of SNP in innate immune receptors for ligand binding, and how we can use our knowledge regarding the innate immune system to design new/optimise existing vaccine strategies.
I graduated from the University of Veterinary Medicine in Hannover (Germany) in 1991, and received a PhD (DrMedVet) in Virology at the University of Zuerich. This was followed by a Marie Curie Research Fellowship in the lab of Chris Howard at the Institute for Animal Health (IAH Compton, UK). During this time, I also passed the exam as Specialist Veterinarian (Fachtierarzt FVH) for Laboratory Medicine and Immunology in Switzerland and gained a Ph.D. in Immunology (University of London). I then moved back to the ETH Zuerich as a group leader and senior scientist, continuing the work started on bovine innate immune cells. In 2001, I was appointed as assistant professor (tenure track) at the Immunology Division at the Institute of Veterinary Virology (University of Bern) under Thomas Jungi, from where I moved to the RVC in 2003.
See Werling Lab - Innate Immune System for more information.
- Dakin, S. G., Werling, D., Hibbert, A., Abayasekara, D. R., Young, N. J., Smith, R. K., Dudhia, J. (2012) Macrophage Sub-Populations and the Lipoxin A(4) Receptor Implicate Active Inflammation during Equine Tendon Repair. PLoS One 7, e32333.
- Schmitz, S., Garden, O. A., Werling, D., Allenspach, K. (2012) Gene expression of selected signature cytokines of T cell subsets in duodenal tissues of dogs with and without inflammatory bowel disease. Vet Immunol Immunopathol 146, 87-91.
- Pagano, S., Satta, N., Werling, D., Offord, V., de Moerloose, P., Charbonney, E., Hochstrasser, D., Roux-Lombard, P., Vuilleumier, N. (2012) Anti-apolipoprotein A-1 IgG in patients with myocardial infarction promotes inflammation through TLR2/CD14 complex. J Intern Med.
- Kathrani, A., Holder, A., Catchpole, B., Alvarez, L., Simpson, K., Werling, D., Allenspach, K. (2012) TLR5 risk-associated haplotype for canine inflammatory bowel disease confers hyper-responsiveness to flagellin. PLoS One 7, e30117.
- Gibson, A., Miah, S., Griebel, P., Brownlie, J., Werling, D. (2012) Identification of a lineage negative cell population in bovine peripheral blood with the ability to mount a strong type I interferon response. Dev Comp Immunol 36, 332-41.