Any infection or systemic disease process (Hypothyroidism, FIV/FeLV,
FCV, pemphigus, pregnancy, renal disease etc.) can contribute to
poor oral cavity health, due to a reduction in the efficiency of
the local immune system and/or poor wound repair and tissue regeneration.
Statistically significant relationships have been found between
myocardial degeneration, kidney disease (both glomerular and interstitial)
and liver parenchymal disease.