Papers
BVD Press Articles
"How BVD can wreak havoc in herd if left unchallenged." An article from the October 2008 edition of "Dairy Farmer", written by Shirley Macmillan. Diary Farmer Oct 2008
BVD Virus Eradication Leaflet, produced in April 2008 by Pfizer Animal Health BVD Virus Eradication Leaflet
"BVD Virus - Eradication from Rutland - What are you doing about it?" A leaflet produced by XL Vets. XL Vets Leaflet
"Is it time to tackle BVD?" - article from December 2007 Cow Management. Cow Management Article
"BVD eradication - the first steps in a thousand have been taken" - article from July 2007 Veterinary Review, written by Richard Gard. Vet Review article
"BVD: We must work towards eradication or be left behind - Devising an eradication strategy that works" - joint article from the 8 June 2007 Farmers Guardian, written by Prof Joe Brownlie & Phil Sketchley. Farmers Guardian June 07 article
"Producers show willing to help eradicate BVD" - article from 18 May 2007 Farmers Weekly. Farmers Weekly Article
"Beating the scourge of Bovine Viral Diarrhoea Virus" - article from 8 December 2006 Farmers Weekly, written by Keith Cutler. Farmers Weekly Dec 06 Article
"UK lagging behind on BVD control" - article from the 24 Nov 2006 Farmers Weekly, written by Chrissie Lawrence. Farmers Weekly article
Papers
Collins, M E, Heaney, J, Thomas, C J & Brownlie, J. (2009) Infectivity of Pestivirus following persistence of acute infection. Vet Micro 138:289-296. Collins_2009_ Vet Micro
Thomas, C, Young, N J, Heaney, J, Collins, M E & Brownlie, J. (2009). Evaluation of efficacy of mammalian and baculovirus expressed E2 subunit vaccines candidates to bovine viral diarrhoea virus. Vaccine 27:2387-2393. Thomas_2009_Vaccine
Young, N J, Thomas, C J, Collins, M E & Brownlie, J. (2006). Real-time RT-PCR detection of Bovine Viral Diarrhoea Virus in whole blood using an external RNA reference. Journal of Virological Methods 138: 218-222 Young_2006_Journal-of-Virological-Methods
Werling, D, Rurik, A, Heaney, J, Moeller, E & Brownlie, J. (2005). Ability to differentiate between cp and ncp BVDV by microarrays: Towards an application in clinical veterinary medicine. Veterinary Immunology & Immunopathology Oct 18; 108:157-164 Werling_2005_Veterinary-Immunology-and-Immunopathology
Young, N J, Thomas, C J, Thompson, I, Collins, M E & Brownlie, J. (2005). Immune responses to non-structural protein 3 (NS3 of bovine viral diarrhoea virus (BVDV) in NS3 DNA vaccinated and naturally infected cattle. Preventative Veterinary Medicine Nov 15; 72:115-120. Young_2005_Preventive-Veterinary-Medicine_1
Stokstad, M., Collins M. E., Brownlie, J. (2004) Analysis of variation of bovine viral diarrhoea virus E2 sequence following transplacental infection of cattle. Vet Microbiol Sep 8; 102(3-4):141-145 Stokstad_2004_Veterinary-Microbiology
Nobiron, I, Thompson, I, Brownlie J & Collins, ME. (2003). DNA vaccination against bovine viral diarrhoea virus induces humoral and cellular responses in cattle with evidence for protection against viral challenge. Vaccine, 2003 May 16; 21(17-18):2091-2101. Nobiron_2003_Vaccine_1
Stokstad, M., Collins M. E., Sorby R., Barboni, P, Meyers, G, Løken T. and Brownlie, J. (2003) The role of a defective interfering particle DI9c in mucosal disease in cattle. Arch Virol Mar 2004; 149(3):571-82
Nobiron, I, Thompson, I, Brownlie, J & Collins, M E. (2001). Cytokine adjuvancy of BVDV DNA vaccine enhances both humoral and cellular immune responses in mice. Vaccine 19:4226-4235 Nobiron_2003_Vaccine
Brownlie, J, Thompson, I & Curwen, A. (2000). Bovine virus diarrhoea virus – strategic decisions for diagnosis and control. In Practice 22:176-187. In Practice Article
Nobiron, I, Thompson, I, Brownlie, J & Collins, M E. (2000). Co-administration of IL-2 enhances antigen-specific immue responses following vaccination with DNA encoding the glycoprotein E2 of bovine viral diarrhoea virus. Veterinary Microbiology 76:129-142. Nobiron_2000_Veterinary-Microbiology
Booth, P J, Collins, M E, Jenner, L, Prentice, H, Ross, J, Badsberg, J H, & Brownlie J. (1999). Association of non-cytopathogenic BVDV with bovine blastocysts: effects of washing, duration of viral exposure and degree of blastocyst expansion. Veterinary Record 144:150-152
Collins, M E, Desport, M & Brownlie, J. (1999). Bovine viral diarrhea virus quasispecies during persistent infection. Virology 259:85-98. Collins_1999_Virology
Booth, P J, Collins, M E, Jenner, L, Prentice, H, Ross, J, Badsberg, J H & Brownlie, J. (1998). Noncytopathogenic bovine viral diarrhea virus (BVDV) reduces cleavage but increases blastocyst yield of in vitro produced embryos. Theriogenology 50: 769-777. Booth_1998_Theriogenology
Brownlie, J, Hooper, L B, Thompson, I & Collins, M E. (1998). Maternal recognition of foetal infection with bovine virus diarrhoea virus (BVDV) - the bovine pestivirus. Clinical and Diagnostic Virology 10:141-150
Desport, M, Collins, M E & Brownlie, J. (1998). Genome instability in BVDV: an examination of the sequence and structural influences on RNA recombination. Virology 246:352-361. Desport_1998_Virology
Brownlie, J, Booth, P J, Stevens, D A & Collins, M E. (1997). Expression of non-cytopathogenic bovine viral diarrhoea virus (BVDV) in oocytes and follicles of persistently infected cattle. Veterinary Record 141:335-337 (plus colour illustrations Veterinary Record 141:425)
Innocent, G, Morrison, I, Brownlie, J & Gettinby G. (1997). A computer simulation of the transmission of immunity and survival of persistently infected animals on the spread of bovine viral diarrhoea virus in dairy cattle. Epidemiol Infect 119(1):91-100
Innocent, G, Morrison, I, Brownlie, J & Gettinby G. (1997). The use of a mass-action model to validate the output from a stochastic simulation model of bovine viral diarrhoea virus spread in a closed dairy herd. Prev Vet Med 31(3-4):199-209. Innocent_1997_Preventive-Veterinary-Medicine
Lindberg, A, Brownlie, J, Gunn, G J, Houe, H, Moennig, V, Saatkamp, H W, Sandvik, T, Valle, P S. (2006). The control of bovine diarrhoea virus in Europe: today and in the future. Rev Sci tech Offic Int Epiz, 25:961-979. Lindberg_Rev Sci tech_2006
Booth, P J, Stevens, D A, Collins, M E & Brownlie, J. (1995). Detection of bovine viral diarrhoea virus (BVDV) antigen and RNA in oviduct and granulosa cells of persistently infected cattle. J Reprod Fert 105:17-24
Brownlie, J & Clarke, M C. (1995). Bovine virus diarrhoea virus (BVDV) biotype distribution in the progress of intestinal lesions. Bull Soc Franco-Japonaise Sci Vet 6: 77-81
Brownlie, J, Clarke, M C, Hooper, L B & Bell, G D. (1995). Protection of the bovine foetus from bovine virus diarrhoea virus by use of a new inactivated vaccine (Torvac-BVD). Vet Record 137:58-62
Brownlie, J. (1994). The management and control of bovine virus diarrhoea virus in cattle herds. Cattle Practice 4:24-36
Desport, M, Collins, M E & Brownlie, J. (1994). Detection of Bovine Viral Diarrhoea Virus RNA by in situ hybridisation with Digoxigenin-Labelled Riboprobes. Intevirology 37:269-276
Howard, C J, Clarke, M C, Sopp, P & Brownlie, J. (1994). Systemic vaccination with inactivated bovine virus diarrhoea virus protects against respiratory challenge Vet. Micro 42:171-179. Howard_1994_Veterinary-Microbiology
Sopp, P, Hooper, L B, Clarke, M C, Howard, C J and Brownlie, J. (1994). Detection of Bovine Viral Diarrhoea Virus p80 protein in subpopulations of bovine leucocytes. Journal of General Virology 75:1189-1194. Sopp_Journal of Gen Viro_1994
Hibberd, R C, Turkington, A & Brownlie, J. (1993). Fatal bovine viral diarrhoea virus infection of adult cattle. Vet Rec 132(9):227
Howard, C J, Clarke, M C, Sopp, P & Brownlie, J. (1992). Immunity to bovine virus diarrhoea virus in calves: the role of different T-cell subpopulations analysed by specific depletion in vivo with monoclonal antibodies. Vet Immunol Immunopath 32: 303-314
Brownlie, J. (1991). The pathways for bovine virus diarrhoea virus biotypes in the pathogenesis of disease. Arch Virol 3:79-96
Brownlie, J. (1990). Pathogenesis of mucosal disease and molecular aspects of bovine virus diarrhoea virus. Veterinary Microbiology 23:371-382
Brownlie, J. (1990). The pathogenesis of bovine virus diarrhoea virus infections. Rev Sci Tech Off Int Epiz, 9:43-59
Brownlie, J & Clarke, M C. (1990). Bovine virus diarrhoea virus: speculation and observations on current concepts. Rev Sci Tech Off Int Epiz, 7:223-230
Desport, M & Brownlie J. (1990). Molecular characterisation of the coding region for p.125 for homologous BVDV biotypes. Arch Virol S3:261-266
Mignon, B, Schwers, A, Waxweiler, S, Boulanger, D, Dubuisson, J, Brownlie, J & Pastoret, P P. (1990). Etude de la stabilite antigenique d’une souche non cytopathogene de virus BVD chez des animaux infectes experimentalement de maniere persistante. Ann Med Vet 134:325-329
Brownlie, J, Clarke, M C & Howard, C J. (1989). Enfermedad de las mucosas-estudios secuenciales sobre la infectividad del virus de la diarrea virica bovina (BVD) sobre el tejido linfatico intestinal. Med. Vet., 6:3-8
Brownlie, J, Clarke, M C & Howard, C J. (1989). Experimental infection of cattle in early pregnancy with a cytopathic strain of bovine virus diarrhoea virus. Research in Veterinary Science 116:307-311
Brownlie, J, Clarke, M C & Howard, C J. (1989). The failure of the cytopathogenic biotype of bovine virus diarrhoea virus to induce tolerance. Immunobiology 4:151
Clarke, M C, Brownlie, J, & Howard, C J. (1989). The effect of immunosuppression with corticosteroid on the infection of calves with bovine virus diarrhoea. Immunobiology 4:151
Howard, C J, Clarke, M C & Brownlie, J. (1989). Protection against respiratory infection with bovine virus diarrhoea virus by passively acquired antibody. Veterinary Microbiology 19:195-203 Vet Micro Paper
Brownlie, J. (1988). Mucosal disease - A pestilence of cattle. Journal of Royal Agricultural Society, England 150:145-152
Brownlie, J, Clarke M C, Howard, C J & Pocock, D H. (1987). Pathogenesis and epidemiology of Bovine Virus Diarrhoea Virus Infection of cattle. Ann Rech Vet 18:157-166
Howard, C J, Brownlie, J & Clarke, M C. (1987). Comparison by the neutralisation assay of pairs of non-cytopathogenic and cytopathogenic strains of bovine virus diarrhoea virus isolated from cases of mucosal disease. Veterinary Microbiology 13: 361-369
Pocock, D H, Howard, C J, Clarke, M C & Brownlie, J. (1987). Variation in the intracellular polypeptide profiles from different isolates of bovine virus diarrhoea virus. Archives of Virology 94:43-53
Howard, C J, Brownlie, J & Thomas, L H. (1986). Prevalence of bovine virus diarrhoea virus viraemia in cattle in the UK. Veterinary Record 119:628-629
Brownlie, J. (1985). Clinical aspects of the bovine virus diarrhoea/mucosal disease complex in cattle. In Practice 7:195-202
Brownlie, J. (1985). BVD - understanding the nature of infection. Proc. British Cattle Veterinary Association 109-111
Howard, C J, Clarke, M C & Brownlie, J. (1985). An enzyme-linked immunosorbent assay (ELISA) for the detection of antibodies to bovine viral diarrhoea virus (BVDV) in cattle sera. Veterinary Microbiology 10: 359-369
Brownlie, J, Nuttall, PA, Stott, E J, Taylor, G & Thomas, L H. (1980). Experimental infection of calves with two strains of bovine virus diarrhoea virus: certain immunological reactions. Veterinary Immunology and Immunopathology 1: 371-378