Sejal Patel
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Biography
Sejal graduated from King's College London with an honours degree in Biomedical Science in 2004. She worked for a few months as a research technician in the department of Investigative Medicine with Professor Steve Bloom at Imperial College London (Hammersmith Hospital Campus). Sejal began her PhD, funded by the Biotechnology and Biological Sciences Research Council (BBSRC) in the same department in October 2005, under the supervision of Professor Mohammad Ghatei and Dr. Kevin Murphy.
Thesis title: Hypothalamic Regulation of Energy Homeostasis and Neuroendocrine Function.
Sejal joined the Royal Veterinary College in May 2009 and is currently working with Dr. Mark Cleasby investigating the role of adiponectin in insulin resistance in skeletal muscle.
Selected Publications
Cleasby ME, Lau Q, Polkinghorne E, Patel S, Leslie SJ, Turner N, Cooney GJ, Xu A, Kraegen EW (2011). The adaptor protein APPL1 increases glycogen accumulation in rat skeletal muscle through activation of the PI3-kinase signalling pathway. The Journal of Endocrinology 210: 81-92
Patel S, Murphy KG, Thompson EL, Patterson M, Curtis AE, Ghatei MA, Bloom SR (2008). Pyroglutamylated RFamide peptide 43 stimulates the hypothalamic-pituitary-gonadal axis via gonadotropin-releasing hormone in rats. Endocrinology 149:4747-54
Smith KL, Patterson M, Dhillo WS, Patel S, Semjonous N, Gardiner JV, Ghatei MA and Bloom SR (2006). Neuropeptide S stimulates the hypothalamo-pituitary-adrenal axis and inhibits food intake. Endocrinology 147:3510-8
Patterson M, Murphy KG, Thompson EL, Patel S, Ghatei MA and Bloom SR (2006). Administration of kisspeptin-54 into discrete regions of the hypothalamus potently increases plasma luteinising hormone and testosterone in male adult rats. Journal of Neuroendocrinology 18:349-54
Dhillo WS, Chaudhri OB, Patterson M, Thompson EL, Murphy KG, Badman MK, McGowan BM, Amber V, Patel S, Ghatei MA, Bloom SR (2005). Kisspeptin-54 stimulates the hypothalamic-pituitary gonadal axis in human males. The Journal of Clinical Endocrinology and Metabolism 90:6609-15.