Nigel Goode
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Nigel is a Senior Lecturer in Veterinary Basic Sciences. Nigel is interested in the theory of education and is currently researching what criteria predict success of students applying to the BVetMed course.
Biography
Nigel graduated with a Bachelor of Veterinary Science from Melbourne University, Australia, in 1982. After working for a year in dairy practice and a couple of years in small animal practice in Australia, Nigel joined the Imperial Cancer Research Fund, now Cancer Research UK. Whilst there he completed a PhD in cell cycle control, which at the time was cutting edge research.
Following his PhD, Nigel moved on to undertake a 4 year Post-doc on Protein Kinase C before joining the Royal Veterinary College as a lecturer in 1993. Nigel is now a Senior Lecturer in Veterinary Basic Sciences and Teaching Coordinator for Veterinary Basic Sciences.
Research
Although Nigel doesn’t get much time for research anymore, he remains interested in cell signalling in its broadest aspects. In particular he enjoys making sense of complexity in science.
Nigel is also interested in the theory of education. As an admissions tutor for the BVetMed course he is researching selection criteria, trying to determine what criteria predict success.
Teaching
Nigel’s key role is Teaching Coordinator for Veterinary Basic Sciences, responsible for organising courses and ensuring their delivery. This role involves driving forwards teaching in terms of new methods and techniques. A particular challenge is engendering student engagement. Nigel has been involved in developing the new BVetMed curriculum. One of his aims for the new curriculum was to decrease the amount of teaching and provide students with more freedom in learning, similar to the structure of the BSc Bioveterinary Sciences course.
Nigel is also BVetMed Year 1 Course Leader and Alimentary Strand Leader for BVetMed.
Selected Publications
SEPULVEDA, M. F., GREENAWAY, E. C., AVELLA, M., GOODE, N. T. & CUNNINGHAM, F. M. (2005) The role of protein kinase C in regulating equine eosinophil adherence and superoxide production. Inflamm Res 54, 97-105. PubMed ID 15883742
RICKARDS, K. J., PAGE, C. P., HAMBLIN, A. S., GOODE, N. T. & CUNNINGHAM, F. M. (2004) Biochemical and functional assessment of equine lymphocyte phosphodiesterases and protein kinase C. Vet Immunol Immunopathol 98, 153-165. PubMed ID 15010224
NAPOLITANO, M., AVELLA, M., GOODE, N. T., BOTHAM, K. M. & BRAVO, E. (2004) Cholesterol esterification in human monocyte-derived macrophages is inhibited by protein kinase C with dual roles for mitogen activated protein kinases. Cell Biol Int 28, 717-725. PubMed ID 15516330
GREENAWAY, E. C., SEPULVEDA, M. F., CUNNINGHAM, F. M. & GOODE, N. T. (2003) Protein kinase C (PKC) isotype profile in eosinophils from ponies with sweet itch and role in histamine-induced eosinophil activation. Vet Immunol Immunopathol 96, 53-63. PubMed ID 14522134
CUNNINGHAM, F. M., VANDERGRIFFT, E., BAILEY, S. R., SEPULVEDA, M. F., GOODE, N. T. & HOROHOV, D. W. (2003) Cloning, expression and biological activity of equine interleukin (IL)-5. Vet Immunol Immunopathol 95, 63-72. PubMed ID 12969637
GREENAWAY, E. C., CUNNINGHAM, F. M. & GOODE, N. T. (2000) Differential localization of protein kinase C isotypes in equine eosinophils and neutrophils. J Leukoc Biol 68, 575-582. PubMed ID 11037981
SMART, N. & GOODE, N. T. (1998) A GFP-PKC fusion protein to investigate the mechanism of PKC down-regulation. Biochem Soc Trans 26, S126. PubMed ID 9649801
PARKER, P. J., BOSCA, L., DEKKER, L., GOODE, N. T., HAJIBAGHERI, N. & HANSRA, G. (1995) Protein kinase C (PKC)-induced PKC degradation: a model for down-regulation. Biochem Soc Trans 23, 153-155. PubMed ID 7758717
GOODE, N. T., HAJIBAGHERI, M. A. & PARKER, P. J. (1995) Protein kinase C (PKC)-induced PKC down-regulation. Association with up-regulation of vesicle traffic. J Biol Chem 270, 2669-2673. PubMed ID 7852335
GOODE, N. T. & PARKER, P. J. (1994) A phorbol ester-responsive PKC-zeta generated by fusion with the regulatory domain of PKC-delta. FEBS Lett 340, 145-150. PubMed ID 8119399
GOODE, N. T., HAJIBAGHERI, M. A., WARREN, G. & PARKER, P. J. (1994) Expression of mammalian protein kinase C in Schizosaccharomyces pombe: isotype-specific induction of growth arrest, vesicle formation, and endocytosis. Mol Biol Cell 5, 907-920. PubMed ID 7803858
GOODE, N. T., MOORE, J. P. & HART, I. R. (1990) Selection and preliminary characterization of variant lines of a murine macrophage tumor resistant to the antiproliferative effects of phorbol esters. Cancer Res 50, 1510-1515. PubMed ID 2105841
GOODE, N. T., MOORE, J. P. & HART, I. R. (1990) Protein kinase C-induced stimulation or inhibition of cellular proliferation in a murine macrophage tumor cell line. Cancer Res 50, 1828-1833. PubMed ID 2106388
GOODE, N. T. & HART, I. R. (1990) Protein kinase C levels and protein phosphorylation associated with inhibition of proliferation in a murine macrophage tumor. J Cell Physiol 142, 480-487. PubMed ID 2312612
HART, I. R., GOODE, N. T. & WILSON, R. E. (1989) Molecular aspects of the metastatic cascade. Biochim Biophys Acta 989, 65-84. PubMed ID 2665818
HART, I. R., GOODE, N. T. & ORMEROD, E. J. (1988) Induction of differentiation as a means of modifying metastatic behaviour. Adv Exp Med Biol 233, 361-365. PubMed ID 3066157