Imelda McGonnell
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Imelda is a Senior Lecturer in Reproduction & Development. Her current research investigates genes that are involved in the differentiation process of neural crest cells and the environmental signals that control their expression, using developing chick and zebrafish models.
Selected Publications
Chantler P. D., Wylie S.R., Wheeler-Jones, C. P., and McGonnell, I. M. (2010) Conventional myosins – unconventional functions. Biophys Rev (In press)
Driver, C. J., Rusbridge, C., Cross H.R., McGonnell, I. M. and Volk, H.A (2010). Relationship of Brain Parenchyma within the Caudal Cranial Fossa and Ventricle Size to Syringomyelia. J Small Animal Practice (In press)
Schmidt C, McGonnell IM, Allen S, Patel K (2008). The role of Wnt signalling in the development of somites and neural crest. Adv Anat Embryol Cell Biol.195:1-64.
Bannister R, McGonnell IM, Graham A, Thorndyke MC, Beesley PW (2008). Coelomic expression of a novel bone morphogenetic protein in regenerating arms of the brittle star Amphiura filiformis. Dev Genes Evol. 218:33-8.
Schmidt, C.*, McGonnell, I.M*#., Allen, S., Otto, A. and Patel K (2007). Wnt6 induces neural crest through the noncanonical signaling pathway. Dev Dyn: 236:2502-11. *joint 1st author. # corresponding author.
Haworth, K. E., Healy, C., McGonnell, I.M., Binns, M. and Sharpe, PT (2007). Characterisation of the genomic loci of canine Fgf-8 locus and screen for genetic variants in 4 dogs with different face types. DNA Seq. 18: 209-19.
Mount, J. G., Muzylak M., Allen, S., Althnaian, T., McGonnell, I. M., Price, J.S. (2006) Evidence that the canonical Wnt signalling pathway regulates deer antler regeneration. Dev. Dyn 235:1390-9.
McGonnell, I.M. and Fowkes, R. (2006). Fishing for gene function – endocrine modelling in zebrafish. J. Endocrinol. 189: 425-39.
Bannister, R, McGonnell, I. M., Graham, A., Thorndyke, M. C. and Beesley, P.W. (2005) Afuni, a novel transforming growth factor-beta gene is involved in arm regeneration by the brittle star Amphiura filiformis. Dev Genes Evol. 215:393-101
Graham, A, Begbie, J. and McGonnell, I.M (2004). The significance of the cranial neural crest. Dev. Dyn. 229: 5-13.
Patruno, M., McGonnell, I.M., Graham, A., Beesley, P., Candia Carnevali, M.D. and Thorndyke, M (2003). AnBMP2/4 is a new member of the TGF-ï¢ superfamily isolated from a crinoid and involved in regeneration. P. Roy. Soc. Lond. B. Bio. 270: 1341-1347.
Vermeren, M., Maro, G.S., Bron, R., McGonnell, I.M., Charnay, P., Topilko, P. and Cohen, J. (2003). Integrity of developing spinal motor columns is regulated by neural crest derivatives at motor exit points. Neuron 37: 403-415.
McGonnell, I.M. and Graham, A. (2002) Trunk neural crest has skeletogenic potential. Curr. Biol. 12: 767-771.
Walshe, J., Maroon, H., McGonnell I.M., Dickson, C. and Mason, I. (2002) Establishment of hindbrain segmental identity requires signaling by Fgf3 and Fgf8. Curr. Biol. 12: 1117-1123.
Chambers, D. and McGonnell, I.M. (2002) Neural crest: Facing the facts of head development. TIGS 18:381-384.