Alberto Malerba
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Selected Publications
Malerba A, Boldrin L, Dickson G. 2011.
LONG-TERM SYSTEMIC ADMINISTRATION OF UNCONJUGATED MORPHOLINO OLIGOMERS FOR THERAPEUTIC EXPRESSION OF DYSTROPHIN BY EXON SKIPPING IN SKELETAL MUSCLE: IMPLICATIONS FOR CARDIAC MUSCLE INTEGRITY. Nucleic acid therapeutics. 21(4):293-298. PubMed ID 21851223
Koo TY, Malerba A, Athanasopoulos T, Trollet C, Boldrin L, Ferry A, Foster H, Popplewell L, Foster K, Dickson G. 2011.
DELIVERY OF AAV2/9-MICRODYSTROPHIN GENES INCORPORATING HELIX 1 OF THE COILED-COIL MOTIF IN THE C-TERMINAL DOMAIN OF DYSTROPHIN IMPROVES MUSCLE PATHOLOGY AND RESTORES THE LEVEL OF a1-SYNTROPHIN AND ß-DYSTROBREVIN IN SKELETAL MUSCLES OF MDX MICE. Human Gene Therapy, 22(11):1379-1388 PubMed ID 21453126
Kang JK*, Malerba A*, Popplewell L, Foster K, Dickson G. 2011.
ANTISENSE-INDUCED MYOSTATIN EXON SKIPPING LEADS TO MUSCLE HYPERTROPHY IN MICE FOLLOWING OCTA GUANIDINE MORPHOLINO OLIGOMER TREATMENT. Molecular Therapy 19:159-164. PubMed ID 20924365
Malerba A, Sharp PS, Graham IR, Arechavala-Gomeza V, Foster K, Muntoni F, Wells DJ, Dickson G. 2011.
CHRONIC SYSTEMIC THERAPY WITH LOW-DOSE MORPHOLINO OLIGOMERS AMELIORATES THE PATHOLOGY AND NORMALIZES LOCOMOTOR BEHAVIOR IN MDX MICE. Molecular Therapy. 19:345-354. PubMed ID 21102560
Malerba A, Pasut A, Frigo M, De Coppi P, Baroni MD, Vitiello L. 2010.
MACROPHAGE-SECRETED FACTORS ENHANCE THE IN VITRO EXPANSION OF DMD MUSCLE PRECURSOR CELLS WHILE PRESERVING THEIR MYOGENIC POTENTIAL. Neurological Research 32:55-62. PubMed ID 19108751
Rossi CA, Pozzobon M, Ditadi A, Archacka K, Gastaldello A, Sanna M, Franzin C, Malerba A, Milan G, Cananzi M, Schiaffino S, Campanella M, Vettor R, De Coppi P. 2010.
CLONAL CHARACTERIZATION OF RAT MUSCLE SATELLITE CELLS: PROLIFERATION, METABOLISM AND DIFFERENTIATION DEFINE AN INTRINSIC HETEROGENEITY. PLoS One 5:e8523. PubMed ID 20049087
Malerba A, Thorogood FC, Dickson G, Graham IR. 2009.
DOSING REGIMEN HAS A SIGNIFICANT IMPACT ON THE EFFICIENCY OF MORPHOLINO OLIGOMER-INDUCED EXON SKIPPING IN MDX MICE. Human Gene Therapy 20:955-965. PubMed ID 19469709
Malerba A, Vitiello L, Segat D, Dazzo E, Frigo M, Scambi I, De Coppi P, Boldrin L, Martelli L, Pasut A, Romualdi C, Bellomo RG, Vecchiet J, Baroni MD. 2009.
SELECTION OF MULTIPOTENT CELLS AND ENHANCED MUSCLE RECONSTRUCTION BY MYOGENIC MACROPHAGE-SECRETED FACTORS. Experimental Cell Research 315:915-927. PubMed ID 19371636
Boldrin L*, Malerba A*, Vitiello L, Cimetta E, Piccoli M, Messina C, Gamba PG, Elvassore N, De Coppi P. 2008.
EFFICIENT DELIVERY OF HUMAN SINGLE FIBER-DERIVED MUSCLE PRECURSOR CELLS VIA BIOCOMPATIBLE SCAFFOLD. Cell Transplantation 17:577-584. PubMed ID 18714677
Vitiello L, Bassi N, Campagnolo P, Zaccariotto E, Occhi G, Malerba A, Pigozzo S, Reggiani C, Ausoni S, Zaglia T, Gamba P, Baroni MD, Ditadi AP. 2008.
IN VIVO DELIVERY OF NAKED ANTISENSE OLIGOS IN AGED MDX MICE: ANALYSIS OF DYSTROPHIN RESTORATION IN SKELETAL AND CARDIAC MUSCLE. Neuromuscular Disorders 18:597-605. PubMed ID 18602263
Zani A, Eaton S, Leon FF, Malerba A, Hall NJ, De Coppi P, Smith VV, Pierro A. 2008.
CAPTOPRIL REDUCES THE SEVERITY OF BOWEL DAMAGE IN A NEONATAL RAT MODEL OF NECROTIZING ENTEROCOLITIS. Journal of Pediatric Surgery 43:308-314. PubMed ID 18280280
Boldrin L, Elvassore N, Malerba A, Flaibani M, Cimetta E, Piccoli M, Baroni MD, Gazzola MV, Messina C, Gamba P, Vitiello L, De Coppi P. 2007.
SATELLITE CELLS DELIVERED BY MICRO-PATTERNED SCAFFOLDS: A NEW STRATEGY FOR CELL TRANSPLANTATION IN MUSCLE DISEASES. Tissue Engineering 13:253-262. PubMed ID 17504060
Fascetti-Leon F*, Malerba A*, Boldrin L, Leone E, Betalli P, Pasut A, Zanon GF, Gamba PG, Vitiello L, De Coppi P. 2007.
MURINE MUSCLE PRECURSOR CELLS SURVIVED AND INTEGRATED IN A CRYOINJURED GASTROESOPHAGEAL JUNCTION. Journal of Surgical Research 143:253-259. PubMed ID 17583740